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Not for customer distribution * Not for customer distribution * Not for customer distribution * Not for customer distribution * Not for customer distribution * Not for customer distribution * Not for customer distribution * Use Animation! Creatinine, the current marker for AKI rises only if the glomerular filtration rate declines which is very late during the continuum of the development of acute kidney injury. Push enter During that time already 50% of the kidney function may be lost. This delay in the diagnosis may prevent a timely treatment of AKI. Push enter Cystatin S is also a marker of glomerular filtration rate, but rises earlier than creatinine Push enter In contrast NGAL rises already very early, at a stage when the kidney is damaged Push enter This is already 48 h earlier compared to the rise of creatinine. The question is now, does this earlier rise matter?? NEXT slide Not for customer distribution * Not for customer distribution * Not for customer distribution * Not for customer distribution * Not for customer distribution * Use Animation! Creatinine, the current marker for AKI rises only if the glomerular filtration rate declines which is very late during the continuum of the development of acute kidney injury. Push enter During that time already 50% of the kidney function may be lost. This delay in the diagnosis may prevent a timely treatment of AKI. Push enter Cystatin S is also a marker of glomerular filtration rate, but rises earlier than creatinine Push enter In contrast NGAL rises already very early, at a stage when the kidney is damaged Push enter This is already 48 h earlier compared to the rise of creatinine. The question is now, does this earlier rise matter?? NEXT slide Not for customer distribution * Not for customer distribution * The Publication from Helga Refsum is a recent (2004) comprehensive review publication, including recommendation in the routine Clinical and Research setting for risk assessments and disease diagnosis also f
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