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Dupuytren’s Disease
Mr G Shyamalan (Shyam)
Hand Surgeon HEFT
So Much Choice!
Benign proliferative disease
Fascia of digits and palm
Nodules, cords and contractures
Definition of Dupuytren’s
Need yes to one of the questions to approve
Moderate MCPJ contracture 30 degrees
Any PIPJ contracture
First web contracture
Procedures of Limited Clinical Effectiveness (POLCE)
Age
Ancestry
Sex
FH
Diabetes
Smoking and Alcohol
Epilepsy
Risk Factors
Dupuytren’s Nodules 50% progress10% require surgery
Trauma
Surgery
Diabetes
No FH
Any race
Generally non-progressive
Non-Dupuytren’s Disease
Male
50
Affected siblings/parents
Ectopic Disease ‘Garrod’s pads’
Bilateral Disease
Dupuytren’s Diathesis
1. Do nothing
2. Radiotherapy – early disease
3. Steroid Injection
4. Percutaneous Needle Fasciotomy
5. Collagenase/Xiapex
6. Limited Fasciectomy
7. Dermato-fasciectomy and skin graft
8. Amputation
Treatment options
1. Do nothing £0
2. Radiotherapy – early disease £2500 (10 visits)
3. Steroid Injection (£ Steroid vial +OPD)
4. Percutaneous Needle Fasciotomy (£ OPD +needle +/- theatres)
5. Collagenase/Xiapex (£760 per vial/digit)
6. Limited Fasciectomy (£2500 plus therapy)
7. Dermato-fasciectomy and skin graft (£3000 plus therapy)
Treatment options cost(2011)
1. Age/Retirement
2. Occupation
3. Hand Dominance
4. Pain
5. The speed of progression of disease
6. Recurrence Vs Extension
7. Extent of contracture PIP joint
8. Diathesis (bilateral, radial side, male)
9. General Systemic Health
10.Patient expectations
Personal thought process
Radiotherapy 3 Gy x5 days- repeat 8 weeks later (potential delayed side effects due to radiation)
Triamcinalone
50% softening
50% recurrence one year
Steroid for nodules
Mostly clinic based
Splint 6 – 12 weeks at night
Low complication rate
Early return to work
5% early failure – akin to a failed injection for CMC joint arthritis!
Long-term 50% recurrence in 5 years but not always requiring surgery
Percutaneous Needle Fasciotomy
Good option for e
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