肺与大肠相表里理论研究进展-济宁医学院学报.docVIP

肺与大肠相表里理论研究进展 于斌1,2，陈孝银2,* (1 济宁医学院中医学教研室 山东 济宁 272067；2暨南大学医学院 广东 广州 510632） 摘要：肺与大肠相表里理论首见于《黄帝内经》，之后在历代医家中得到验证和推广，并将其应用于肺肠相关疾病的诊断和治疗。肺肠相关性主要体现在气机升降和水液代谢方面，本文首先对这种调节关系的机制研究进行阐述，其次从肺肠同源性、神经内分泌免疫机制以及症候关联方面进行现代研究的概述，从而为今后的研究提供一定的价值参考。 关键词：肺与大肠相表里，进展 [中图分类号] R223.1+1 Research progress on exterior-interior correlation between the lung and large intestine theory Yu Bin 1,2, Chen Xiaoyin 2,* (1. Jining Medical University, Jining, 272067, China. 2. School of Medicine, Jinan University, Guangzhou, 510632, China.) Abstract: The exterior-interior correlation between the lung and large intestine theory was first induced by Inner Canon of Yellow Emperor, and this theory was verified in the past dynasties after a promotion, and applied to the diagnosis and treatment of intestinal lung related diseases. The correlation of lung and the larger intestine is mainly reflected in the flow of Qi’s ascending and descending and water metabolism. In this paper, the study progress on these aspects were described firstly and then the mechanism of Lung and large intestine theory on homology theory, neuroendocrine immune system and symptom correlation were also been elaborated. The aim of this paper was to provide a value reference for the future research on exterior-interior correlation between the lung and large intestine theory combining with modern research progress. Keywords: Exterior-interior correlation between the lung and large intestine theory; research progress 作者简介：于斌，男（1984-），研究方向：外感病及脾胃病的中西医结合诊断和治疗。 *通讯作者：陈孝银，博士研究生导师，研究方向：外感病病因病机，Email：tchenxiaoyin@jnu.edu.cn. 基金项目：国家自然科学基金；山东省自然科学基金（ZR2014HQ051）；济宁市2015年度中医药科技计划（ZYY2015030）。 “肺与大肠相表里”的理论是中医学藏象学说的基本内容之一，其提出首见于《内经》，在《灵枢·本输》记载：“肺合大肠，大肠者，传导之腑”，《灵枢·经脉》中记载肺手太阴经和手阳明大肠经的络属关系，其言：“肺手太阴之脉，起于中焦，下络大肠，还循胃口，上膈属肺……，大肠手阳明之脉，起于大指次指之端……下入缺盆，络肺，下膈，属大肠”，从而奠定了“肺与大肠相表里”的理论基础，二者的关系主要体现在气机升降和水液代谢方面，与呼吸功能和排便功能相关，肺气宣发肃降功能正常，则大肠传导正常，大便通畅；如肺失肃降，津液不能输布到肠腑，导致大便秘结；同样大肠腑气不通，影响到肺气的宣降，导致肺气不利而发生咳喘。“肺与大肠相表里”的理论提出后，在并