重要经典化学反应及其机理重经典化学反应及其机理重要经典化学反应及其机理重要经典化学反应及其机理.doc

-? Aromatic Reactions - Condensation -? Cyclization? -?Epoxide Transformation - Olefination? -? Oxidation -? Reduction? -? Rearrangement ? Condensation ? Olefination????? Oxidation??????? Rearrangement??? Reduction???? Cyclization???? ?Aromatic Reactions???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????? top ? ? Common Transformation of Epoxide???????????????????????????????????????????????????????????????????????????????????????? ?top ??????????? ...a recent memoir by a Herr vant Hoff on the Arrangements of Atoms in Space, a document crammed to the hilt with the outpourings of a childish fantasy...This Dr. J.H. vant Hoff...no taste for accurate chemical research... By H. Kolbe (one of the most eminent organic chemist of the time).? 10 years later vant Hoff was named the first recipient of the Nobel Prize in Chemistry. A ?Acetoacetic Ester Synthesis is a very useful basic reaction in ether industry or academia. The methylene group in acetoactic ester could be easily alkylated, and double alkylated under basic condition. One condition I used frequently is acetone as solvent, K2CO3 as base, and alkyl bromide as alkylation reagent. The reaction rarely lets me down. Simonsen, J.L.; Storey, R. J. Chem. Soc. 1910, 95, 2106Simonsen, J.L.; Storey, R. Proc. Chem. Soc. 1910, 25, 290?? Click here to learn more. Alder (Ene) Reaction is thermal or catalytic sigmatropic rearrangement with H-trasfer and carbon bond formation. ? Click here to learn more. Aldol condensation is a reaction that generated lots of Ph.D. in organic synthesis. No need to talk about it. The aldol condensation using aldehyde and silyl enol ether as starting materials, and lewis acid, like TiCl4, as catalyst is called Mukaiyama aldol condensation. ? Kane, R. Ann. Phys. Chem. Ser. 2 1838, 44, 475Kane, R. J. Prakt. Chem. 1838, 15, 129??????????????????? Click here to learn more. Algar-Flynn-Oyamada Reaction is the sy