2015年度广西科学技术奖推荐项目公示-华东师范大学科技处.doc

2016年度广西科技技术奖推荐项目公示表 项目名 称 肿瘤生物靶向治疗新理论与新技术 拟推荐单位 广西壮族自治区教育厅 项目简介 1. 所属学科: 2. 基金来源: 国家自然科学基金NoNo 3. 研究方法: 4. 主要发现 5. 科学价值： 知识产权情况 论文专著目录 Zhuo H, Peng Y#, Yao Q#, Zhou N, Zhou S, He J, Fang Y, Li X, Jin H, Lu X*, Zhao Y*. Tumor imaging and interferon-γ-inducible protein-10 gene transfer using a highly efficient transferrin-conjugated liposome system in mice. Clinical Cancer Research. 2013; 19(15): 4206-17. (SCI) Lu X#, He J#, Li X#, Zhao Y*. The relationship between malignant and tumor-associated cells provides a new strategy for targeted diagnosis and therapy. Oncoimmunology. 2013; 2(11): 26295. (SCI) Mongkhoune S#, Xie Y#, Wang Y#, Chen Y, Zhou N, Peng Y, He J, Yu X, Zhou S, Luo G, Zhao Y, Lu X*. A constructed HLA-A2-restricted pMAGE-A1(278-286) tetramer detects specific cytotoxic T lymphocytes in tumour tissues in situ. Journal of International Medical Research. 2013; 41(6): 1811-24. (SCI) Yu X#, He J#, Mongkhoune S#, Peng Y, Xie Y, Su J, Zhou S, Xie X, Luo G, Fang Y, Li X, Li X, Zhou N*, Zhao Y*, Lu X*. Artificial antigen-presenting cells plus IL-15 and IL-21 efficiently induce melanoma-specific cytotoxic CD8+ CD28+ T lymphocyte responses. Asian Pacific Journal of Tropical Medicine. 2013; 6(6): 467-72. (SCI) Du B#, Luo W, Li R, Tan B, Han H, Lu X, Li D, Qian M, Zhang D, Zhao Y*, Liu M*. Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression. Journal of Biological Chemistry. 2013; 288(21): 15131-41. (SCI) Zhang L#, Yang M#, Gan L, He T, Xiao X, Stewart MD, Liu X, Yang L, Zhang T, Zhao Y*, Fu J*. DLX4 upregulates TWIST and enhances tumor migration, invasion and metastasis. International Journal of Biological Science. 2012; 8(8): 1178-87. (SCI) Li D#,*, Qiu Z#, Shao Y, Chen Y, Guan Y, Liu M, Li Y, Gao N, Wang L, Lu X, Zhao Y*, Liu M*. Heritable gene targeting in the mouse and rat using a CRISPR-Cas system. Nature Biotechnology. 2013; 31(8): 681-683. (SCI) Lu X#, Qiu Z#, Wan Y#，