PowerPointPresentation-InsulinPast,Present,andFuture.ppt

Changes In Diabetes CareA History Of Insulin PumpsPast, Present, and Future John Walsh, P.A, C.D.E.jwalsh@ Online slide presentation What We Will Cover Early history of diabetes Discovery of insulin When insulin was found to not be the full answer High glucose as the culprit Lack of change in the A1c since the DCCT Why the dumb insulin pump has not helped What smart pumps offer The promise of intelligent devices The Super Bolus How simple and intelligent timers can help Screen shots from an intelligent device In 1500 BCDiabetes First Described In Writing Hindu healers wrote that flies and ants were attracted to urine of people with a mysterious disease that caused intense thirst, enormous urine output, and wasting away of the body 250 BCThe Word Diabetes First Used Apollonius of Memphis coined the name diabetes” meaning to go through or siphon. He understood that the disease drained more fluid than a person could consume. Gradually the Latin word for honey, mellitus, was added to diabetes because it made the urine sweet. Early Diabetes Treatments In 1000, Greek physicians recommended horseback riding to reduce excess urination In the 1800s, bleeding, blistering, and doping were common In 1915, Sir William Osler recommended opium Overfeeding was commonly used to compensate for loss of fluids and weight In the early 1900s a leading American diabetologist, Dr. Frederick Allen, recommended a starvation diet Early Research In 1798, John Rollo documented excess sugar in the blood and urine In 1813, Claude Bernard linked diabetes to glycogen metabolism In 1869, Paul Langerhans, a German medical student, discovered islet cells in the pancreas In 1889, Joseph von Mehring and Oskar Minkowski created diabetes in dogs by removing the pancreas In 1910, Sharpey-Shafer of Edinburgh suggested a single chemical was missing from the pancreas. He proposed calling this chemical insulin. Near Miss In 1908, a young internist in Berlin, Georg Ludwig Zuelzer created a pancreas e