320排CT灌注成像在肝癌诊断中的临床应用.PDF

· 562 · tChina，Vo1．15，No．6，Nov．2013 丕直垦堕匿垫 生 旦箜 鲞箜 塑 些 翌 ! ! 0f !heas — — · 论 320排 CT灌注成像在肝癌诊断中的临床应用 邱国钦，刘昌华，陈玉强，吴贵华 【摘要] 目的 探讨 320排CT灌注成像(CTPI)在原发性肝癌 (PLC)的血流灌注特点及其诊断价值。方法 对 103例 PLC于介人治疗前行320排CT全肝灌注扫描，获得灌注彩图及其参数，并与正常肝组织比较，评价PLC的cT灌注特点。结 果 103例PLC在肝动脉灌流量 (HAP)彩图上较周围正常肝组织呈明显高灌注，其中34例呈均匀高灌注，69例呈不均匀高 灌注；PLC在门静脉灌流量 (PVP)彩图上较正常肝组织呈明显低灌注；肿瘤组织的BF、BV、PS、HAP、HPI参数值均高于肝组织 (P0．05)，而MTT、PVP低于肝组织(P0．05)。结论 320排 CTPI能直观、定量地全面反映PLC的血流灌注特点，有助于 介入治疗前对PLC作出快速而准确的诊断与评价。 [关键词] 肝癌；320排CT；灌注成像 ；诊断 [中图分类号] R735．7 [文献标志码] A doi：10．3969／j．issn．1672-271X．2013．06．004 Theclinicalapplicationof320rowsCT perfusionimaginginlivercancerdiagnosis QIUGuo—qin，LIUChang—hua，CHENYu—qiang，WUGui—hua． ChenggongHospitalAffiliatedtoXiamenUniversity，174Hospitalof PIA，Xiamen，Fujian361003，China [Abstract] 0bjective Toexplorethebloodperfusionanditsdiagnosisvalueof320rowsCTperfusionimaginginprimaryliv— ercancer．Methods Toconduct320rowswholeliverperfusion scantoPLCsufferersbeforeinterventionaltherapy，toacquiretheir perfusioncolordrawingsandparameters．andthencomparedtonormallivertissuetoevaluatePLC perfusionfeatures．Results For those103sufferers，theirPLCinHAPcolordrawingshowobviouslyhighperfusionthannormallivertissue．Amongthem，34show even— lyhighperfusionbut69show unevenlyhighperfusion．TheirPLC inPVPcolordrawingshowsobviouslylowperfusion．BF，BV，PS，HAP andHPIparametersoftumortissuearehighthanlivertissue(P0．05)，butMTIandPVParelowthanlivertissue(P0．05)．Con- clusion Wholeliverfourdimensionsperfusionanalysison320rowsCIPIcanfullyreflectPLCgbloodperfusionfeaturesdirectlyand measurably．ItcanmakeaquickandcorrectdiagnosisandevaluationO13PLC beforeinterventionaltherapy． [Keywords] livercancer；320rowsCT；perfusionimaging；diagnosis 320排 CT灌注成像 (CTperfusionimaging