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BalloonAngioplastyfor
Balloon Angioplasty for Intracranial Atherosclerotic Disease
Periprocedural Risks and Short-Term Outcomes in a Multicenter Study
Thanh N. Nguyen, MD; Osama O. Zaidat, MD; Rishi Gupta, MD; Raul G. Nogueira, MD;
Nauman Tariq, MD; Junaid S. Kalia, MD; Alexander M. Norbash, MD; Adnan I. Qureshi, MD
Background and Purpose—Whether stenting is superior to angioplasty in the treatment of intracranial atherosclerotic
disease is unknown. Dissections, vessel rupture, and lesion recoil observed with primary angioplasty using balloon
catheters designed for coronary arteries have undermined the role of primary angioplasty as a preferred treatment for
intracranial atherosclerotic disease. The goal of this study is to report the immediate and 3-month outcomes of treating
patients with intracranial atherosclerotic disease with angioplasty balloon catheters in a multicenter study.
Methods—This is a retrospective review of 74 patients from 4 institutions treated with primary angioplasty for intracranial
atherosclerotic disease over a 6-year time period. Technical success (residual stenosis 50%), periprocedural success
(no vascular complication within 72 hours), and 3-month outcomes are reported.
Results—The mean degree of stenosis pretreatment was 79%14% and reduced to 34%18% after angioplasty. Technical
success was achieved in 68 (92%; 95% CI, 83% to 97%) of the 74 patients. Periprocedural success was achieved in 65
(88%; 95% CI, 78% to 94%) of the 74 patients. There were 4 (5%; 95% CI, 1.5% to 13%) major procedure-related
strokes, 2 of which resulted in death within 6 hours of the procedure. The 30-day stroke/death rate was 5% (4 of 74;
CI, 1.5% to 13%). Three-month follow-up was available in 71 patients. In this interval, 2 patients had new stroke, 1 in
the ipsilateral territory and the other in the contralateral territory. The 3-month stroke or death rate was 8.5% (6 of 71;
CI, 3.1% to 17.5%); the retreatment rate was 2.8% (2 of 71; CI, 0.3% to 10%).
Conclusion—Balloon angiopla
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