Harvard School of Public Health Authors.pdf

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Harvard School of Public Health Authors

Trends in Smoke Nicotine Yield and Relationship to Design Characteristics Among Popular U.S. Cigarette Brands 1997-2005 A Report of the Tobacco Research Program Division of Public Health Practice Harvard School of Public Health Authors Gregory N. Connolly, DMD MPH Hillel R. Alpert, ScM BSc Geoffrey Ferris Wayne, MA Howard Koh, MD, MPH January, 2007 Supported by American Legacy Foundation and National Cancer Institute 2 ABSTRACT Objective: We sought to determine whether smoke nicotine yields of cigarettes would show an overall increase over time or an increasing trend limited to any particular market category (e.g. full flavor vs. light, medium (mild), or ultralight; mentholated vs non- mentholated), manufacturer, or brand family or brand style, and smoke nicotine yields would be associated with measurable trends in cigarette design. Methods: Machine-based measures of smoke nicotine yield as well as measures of cigarette design features related to nicotine delivery (ventilation, nicotine content in the tobacco rod, and number of puffs), and market category descriptors were obtained from annual reports filed with the Massachusetts Department of Public by tobacco manufacturers for the years 1997-2005. Trends in smoke nicotine yield and relationship with design features and market parameters were analyzed with multilevel mixed effects regression modeling procedures. Results: A statistically significant trend was confirmed in increased smoke nicotine yield of 0.019 mg per cigarette (1.1%) per year over the period 1997-2005 or 0.029 mg per cigarette (1.6%) per year over the period 1998-2005. The increasing trend was observed within all major market categories (mentholated vs. non-mentholated and full flavor vs. light, medium (mild), or ultralight). Smoke nicotine yield was positively associated with nicotine concentration in the tobacco and number of puffs per cigarette, both of which also showed increasing trends during t

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