07_实验记录常用英文表达句型.pdf

实验记录常用英文表达句型 一、 加料过程常用表述 1. 添加试剂 2. 催化量的 3. 气体保护 4. 通入气体 5. 通过双针头导管加料 6. 通过注射器加料 二、 反应过程常用表述 1. 反应检测 2. 放置过液 3. 甲苯/乙醇带水 4. 氢化反应 5. 分水器 6. 反应放热 7. 微波反应 三、 后处理过程常用表述 1. 过滤 2. 淬火 3. 磨碎 4. 在两相中分开 5. 静止固化 6. 在冻干机冻干 7. 纯化 过柱 制备 HPLC 纯化 制备 TLC 纯化 重结晶 8. 调 PH 9. 萃取 10. 浓缩 11. 干燥 干燥 真空干燥 四、 部分常见反应现象描述 1. 加料放热 2. 反应过程中或者降温有固体析出 3. 加料不溶解 4. 反应变粘稠/变色 五、 特殊结果叙述 1. 无进一步处理 2. 统一和其他批次一起后处理 3. 检测条件，不需要后处理 1 一、加料过程常用表述 1.添加试剂 To a mixture (suspension / solution / slurry) of compound 12 (487 mg, 1 mmol) and o-plenylenediamine (948 mg, 6 mmol) in CH2Cl2 (15 ml) being coolen to 0℃ was added the DCC (226 mg, 1.1 mmol). Anhydrous lithium iodide (1.38 g, 10.3 mmol) was added the five portions (dropwise / in one portion / in portions) to a stirred solution of compound 12 (10.90 g, 51.5 mmol) in CH2Cl2 (120 ml). A round-bottom flask was changed with compound 3 (1.75 g, 5.27 mmol), LiCl (1.17 g, 26.3 mmol), DMSO (100 Ml) and H2O (378 ul) 分批加入 in portions/portionwise 一次性加入 in one portion 滴加 dropwise 2.催化量的 Et3N (20 mL, 142 mmol) and a catalytic amount of DMAP were added the solution of compound 1 (4.549 g, 46.4 mmol) in CH2Cl2（120 ml） at 0℃ 3.气体保护 To a stirred -78 solution ℃ of trimethylsilyacetylene (4.44g, 45.5 mmol)in THF (10 ml) under argon was added dropwise n-butylithium (1.6M in hexane, 28.25 ml). 4.通入气体 An ozone-enrichen steam of oxygen was bubbled through a cold (-78 ) solution of ℃ compound 9 (128 mg, 1.409 mmol) in CH2Cl2 (5 ml) until it turned light blue. The solution was purged with argon at -78 for 10 min to remove the excess O℃ 3 . 5.通过双针头导管加料 The mixture was added to a sulotion of compound 2 (3.00 g, 12.8 mmol) in THF (48 ml) via cannula over a period of 30 min. A solution of compound 29 (100 mg, 0.19 mmol, 1.0 equiv) in dry DMSO (1.5 ml) was cannulated under argon to a vigorously stirred mixture of powered potassium superoxide (62 mg, 0.87 mmol, 4.5 equ