Quantitative risk assessment of human campylobacteriosis.pdf

International Journal of Food Microbiology 128 (2008) 274–287 Contents lists available at ScienceDirect International Journal of Food Microbiology j ourna l homepage: www.e lsev ie / locate / i j foodmicroQuantitative risk assessment of human campylobacteriosis related to the consumption of chicken meat in two Italian regions Paolo Calistri ?, Armando Giovannini Istituto Zooprofilattico Sperimentale dellAbruzzo e del Molise “G. Caporale”, Via Campo Boario, 64100 Teramo, Italy? Corresponding author. E-mail address: p.calistri@izs.it (P. Calistri). 0168-1605/$ – see front matter ? 2008 Elsevier B.V. Al doi:10.1016/j.ijfoodmicro.2008.08.021a b s t r a c ta r t i c l e i n f oArticle history: Campylobacteriosis is the m Received 3 December 2007 Received in revised form 4 August 2008 Accepted 28 August 2008 Keywords: Campylobacter Quantitative risk assessment Chicken meat Italyost frequently reported zoonotic disease in humans within the European Union. The consumption of contaminated chicken meat is considered one of the main sources of human infection. Although there are no official data on the incidence of Campylobacter infection in Italy, the available studies suggest that this infection is a major problem also in Italy. The authors developed a simulation model to quantitatively estimate the expected annual number of human cases of campylobacteriosis in the Italian regions of Abruzzo and Molise, due to the cross-contamination during the handling of Campylobacter jejuni contaminated chicken meat in domestic kitchen. The authors considered two different models for the dose– response relationship, given their crucial effects on the models outputs. The expected percentage of human population, experiencing Campylobacter gastroenteritis episodes every year in Abruzzo e Molise regions, varied between 0.8% and 1.8%, according to the dose–response model. ? 2008 Elsevier B.V. All rights reserved.1. Introduction The incidence of thermophilic Campylobacter human infections in th