Chapter4CartilageandBone.pptVIP

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Chapter4CartilageandBone

组织胚胎学课件 七年制英文医学班专用; Chapter 4 Cartilage and Bone ; 1. Cartilage: organ=Cartilage tissue+perichondrium ;1)????? structure of cartilage tissue ---cell: chondrocyte ---cartilage matrix ;①???? chondrocyte: ---Structure: LM embedded in cartilage lacuna peripheral cells: --small and immature --single and flattened central cell: --large and mature, --round and in group of 2-8 cells --small and round nucleus --basophilic cytoplasm --EM: rich in RER and Golgi complex ;*isogenous group: several cells locates in one lacuna, which are derived from a single(same) parent cell ; ②???? Cartilage matrix ---ground substance: proteoglycan: --same to loose CT --there are more chondroitin sulfate distributed at the periphery of cartilage lacuna---called as cartilage capsule(basophilic) chondronectin water ---fiber: type and number of fiber depends on the type of cartilage ;2) Classification: according to the fiber Hyaline cartilage: less collagenous fibril←type II collagen articular surface, rib cartilage, trachea and bronchi ;Fibrous cartilage: large amount of collagenous fiber bundles cells are small and less intervertebral disc, symphysis pubis ;Elastic cartilage: large amount of elastic fiber external ear, epiglottis ; 3) perichondrium two layers: ---out layer: contain more fiber-protection ---inner layer: more cells-osteoprogenitor cell(fusiform in shape) ;4) growth of cartilage ---interstitial growth: inner chondrocyte proliferation→ produce fiber and matrix. immature cartilage ---appositional growth: osteoprogenitor cell→cartilage cell (chondrocyte) → produce fiber and matrix. growing and mature cartilage ;2.Bone ---consists of bone tissue, periosteum and endosteum, bone marrow ;1)????? Bone tissue ① Cells: ;a. osteoprogenitor cell: stem cell ---structure: fusiform, small ovoid nucleus slight basophilic cytoplasm exist in periosteum and endosteum

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