血乳酸检测对引起呼吸衰竭常见疾病的临床指导意义.pdfVIP

窑综 述 窑 中国当代医药 2015年 1月第22卷第 1期 血乳酸检测对引起呼吸衰竭常见疾病的 临床指导意义 王彩云1 吴允萍2 王 东2 张东岳2 班丽红1 刘 巍2银 1.甘肃中医学院临床医学系2012级在读硕士研究生袁兰州 730000曰2.兰州市第一人民医院呼吸科袁兰州 730050 [摘要] 血乳酸浓度反应全身组织灌注情况袁是细胞缺氧的敏感标志物袁在组织灌注不良及低氧等情况下血乳酸 明显增高遥 当灌注不良得到有效控制袁低氧状态迅速纠正后袁体内乳酸水平迅速降低遥 呼吸衰竭患者体内病理生 理变化的一个主要方面就是组织细胞的氧供不足袁导致血乳酸升高袁甚至血乳酸中毒袁本文旨在综述检测血乳酸 浓度对引起呼吸衰竭常见疾病的临床指导意义袁为临床上对此类疾病治疗方案的合理选择提供参考遥 [关键词] 血乳酸曰呼吸衰竭曰临床意义 [中图分类号] R563.8 [文献标识码]A [文章编号] 1674-4721渊2015冤01渊a冤-0190-03 Clinical significance of the blood lactate on the common disease which cause respiratoryfailure 1 2 2 2 1 2银 WANG Cai-yun WUYun-ping WANGDong ZHANG Dong-yue BAN Li-hong LIU Wei 1.2012Postgraduate Student,Department of Clinical Medicine,Gansu College of Traditional Chinese Medicine,Lanzhou 730000,China曰2.Departmentof Respiration,theFirstPeople忆sHospitalof Lanzhou City,Lanzhou 730050,China [Abstract] Blood lactate concentration reacted to body tissue perfusion is a sensitive marker for cells under hypoxia.It increased significantlywhen the body isinapoor perfusion andlow oxygen.Whenhypoperfusion has been controled ef鄄 fectively,and hypoxia quicklyhas been corrected,the level of lactic acid in vivo decreased rapidly.The lack of oxygen is a major aspect of respiratory failure pathophysiological changes,which causing the blood lactic acid increased,further鄄 more blood lactic acidosis.The purpose of this review is to detect blood lactic acid and to analyse of the test results.In the end,we summarized clinical significance of blood lactic acid in the common disease of respiratory failure and pro鄄 vided rational clinicaltherapyfor suchdiseases. [Keywor