1,6二磷酸果糖联合香丹注射液治疗新生儿缺氧缺血性脑病合并心肌损害.docVIP

KKME---专业医学有哪些信誉好的足球投注网站引擎/ 1，6-二磷酸果糖联合香丹注射液治疗新生儿缺氧缺血性脑病合并心肌损害 作者：李隽英，元会英 作者单位： 054100 河北沙河，沙河市医院 ［摘要］ 目的 观察1，6-二磷酸果糖（FDP）联合香丹注射液对新生儿缺氧缺血性脑病合并心肌损害的临床疗效。方法 76例新生儿缺氧缺血性脑病合并心肌损害患儿随机分为两组，治疗组40例在常规治疗基础上采用1，6-二磷酸果糖联合香丹注射液治疗。对照组36例采用常规治疗。结果 治疗组总有效率及临床症状改善均优于对照组，两组间差异有显著性（P＜0.05）。结论 1，6-二磷酸果糖联合香丹注射液对新生儿缺氧缺血性心肌损害有良好疗效。 ［关键词］ 1，6-二磷酸果糖；香丹注射液；新生儿；缺氧缺血性脑病；心肌损害 Fructose1，6diphosphate combined with injection of salvia miltiorrhiza compound in the treatment of neonate hypoxicischemic encephalopathy with myocardial injury LI Junying，YUAN Huiying.The Hospital of Shahe,Shahe 054100，China ［Abstract］ Objective To observe the clinical effect of fructose1,6diphosphate combined with injection of salvia miltiorrhiza compound in the treatment of neonate hypoxicischemic encephalopathy with myocardial injury.Methods 76 patients with HIE complicated with myocardial injury were divided into two groups,experimental group and control group.40 cases in the experimental group were treated with FDP combined with injection of salvia miltiorrhiza compound,36 cases were treated with routine treatment.Results There was remarkable difference between them both in the total efficient rate and recovery of clinical symptoms.Conclusion FDP combined with injection of salvia miltiorrhiza compound are effective in treating myocardial injury of HIE. ［Key words］ fructose1,6diphosphate;salvia miltiorrhiza compound;newborn;hypoxicischemic encephalopathy;myocardial injury 新生儿缺氧缺血性脑病由于缺血缺氧可引起体内各脏器血液灌注的改变而导致多脏器损害，心脏是受损的脏器之一。大多数窒息缺氧心肌损害的病变可以逆转，应予以积极治疗。我院于2001年7月～2005年8月收治新生儿缺氧缺血性脑病合并心肌损害患儿76例，应用1，6-二磷酸果糖联合香丹注射液治疗40例，取得满意疗效，现报告如下。 1 资料与方法 1.1 一般资料 2001年7月～2005年8月我院收治新生儿缺氧缺血性脑病合并心肌损害足月新生儿76例，全部病例均符合1996年中华医学会儿科学会新生儿学组的新生儿缺氧缺血性脑病的诊断依据及临床分度［1］。心肌损害诊断标准［2］：（1）除外宫 内病毒感染；（2）具有紫绀、呼吸增快、皮肤苍白、哭声弱、心音低钝、心率减慢或心率增快及肝脏增大等 症状及体征；（3）心电图：T波低平或倒置，ST段移位及Q波异常；（4）血清肌酸激酶同工酶（CPK-MB）显著增高（25 u/L）。治疗组40例，男26例，女14例，胎龄37～42周，平均（39.1±1.59）周；日龄1～2