国产与进口头孢吡肟治疗急性泌尿系统感染的成本-效果分析.pdfVIP

重庆医学2006 年12 月第35 卷第24 期 2261 ·临床研究· 国产与进口头孢吡肟治疗急性泌尿系统感染的成本-效果分析 李国成，陈清霞，陈广惠，杨 鸿 （中山大学附属第二医院，广州510120 ） 摘 要：目的 比较国产与进口头孢吡肟治疗急性中重度泌尿系统感染的经济效果。方法 将122 例病例随机分为两组，A 组（使用国产药）61 例，B 组（使用进口药）61 例，运用药物经济学方法进行成本效果分析。结果 A 、B 两组治疗方案的有效率分 别为98. 36% 和96. 72% ，致病菌清除率均接近100% ，两组药物不良反应发生率分别为6. 56% 和10. 47% 。两组对比差异均无统 计学意义（P 0. 05 ）。成本效果比（C / E ）分别为4 059. 64 和4 625. 45 ，与国产头孢吡肟组相比，进口头孢吡肟组每增加一个单位 效果需多花费29 309. 74 元。结论 综合考虑，国产头孢吡肟对泌尿系统感染的经济效果优于进口药。 关键词：头孢吡肟；泌尿系统感染；成本效果分析 中图分类号： R983 文献标识码：A 文章编号：1671 8348（2006 ）24 2261 02 Cost-effectiveness analysis of domestic and imported cefepime in treatment of acute urinary infections LI Guo cheng ，CHEN Oing xia，CHEN Guang hui，et al. （Second Hospital Attached to Zhongshan Uniuersity ，Guangzhou 510120 ，China ） Abstract ：Objective To compare the cost effectiveness between domestic and imported cefepime in the treatment of acute urinary in fections. Methods One hundred and twenty patients were randomiy divided into 2 groups. There were 61 cases in domestic group （A group ）and 61 cases in imported group （B group ）. Principie of pharmacoeconomics was adopted to anaiyze cost effectiveness. Results The effective rates of A group and B group were 98. 36% and 96. 72% ，the bacteriai eradiction rate both was 100% ，and the incidence of ad verse reaction was 6. 56% and 10. 47% respectiveiy. The difference was not significant between two groups（P 0. 05 ）. The cost effective ness ratio（C / E ）were 4 059. 64 and 4 625. 45 respectiveiy. The cost for every one unit increment of effectiveness for B group was RMB 29 309. 76 yuan more than that of A group. Conclusion Taking