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川芎嗪、冰片对纤毛持续运动时间的影响.pdf
Ginc R剧, 1996 , 79 (1∞) :2029 却35. 杂志, 2∞2 , 10(2) :149-151.
[8J 周金,苗鳞穗,张颖.老年 2 型糖尿病患者颈动脉内腰 (2005 -12 -29 收稿)
中居厚度与心血管病危险因素的关系.中国动脉硬化
Protec创刊配何时t of Effective Parts of Zingiber 0町ecinal on Vascular
Endothelium of the Experimental Hyperlipidemic Rats
WU Cai-xia1 , WEI Xin巾 ing 1 , DlNG Hua1 , SUN Xia1 , CHENG Xiu-min2
(1. Department of Pharmacology , School of Medicine Shandong University , Jinan 25∞ 12 , China; 2 嗣 Shandong Medical College , Li-
nyi 276002 , China; 3. Pharmaceutical School of Shandong University , Jinan 25∞ 12 , China)
Abstract 0均 ective: To observe the influence of effective parts of Zingiber Otlìcinale on serum IL -6、 TNF-αin oroler to investi?
gate the protctive effects of the effec吐 ive 阴阳 of Zingiber Otlìcinal (EPZ) on endothelium of the experimental hyperlipidemic rats and
the mechanism of its effects. Methods: The hyperlipidemia model of rals was constructed by feeding high也.t forage and filled with the
effective parts of Zingiber Otlìcinale 2∞ mglkg 、4ωmglkg 、 8ωmglkg every day for 13 weeks. Blood was drawn to determine bo由出e
level of serum IL而 and TNF-α. All the aortaes were taken to oberserve morphologic change and the intima-media thickness were detec?
ted. Results: The effective parts of Zingiber Officinale could markedly decrease intima-m叫 ia thicknes 白, but had no marked influence
in the level of serum IL-6 and TN孔 α. ConcIusion:ηle Effect Parts of Zingiber Officinale has the effect of protection of the endothelia
of hyperlipidemia rats , which has nothing wi由 the level of serum IL-6 and TNF-α.
Key words Effective Parts of Zingiber 0征icinale; Hyperlipidemia; Rat; Vascular endothelium; Inflammatorγfactor; Intima?
media thickness.
川笃嗦、冰片对纤毛持续运动时间的影响
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