常用4种抗高血压药治疗原发性高血压的成本-效果分析.pdfVIP

常用 4 种抗吝血压药治疗才在友性高血压的成本-效果分析 谭业慧\黄齐亮(佛山市南海区桂城医院，广东佛山 5282∞) 中图分类号 R972 .4 文献标志码 B 文章编哥 1672 -2124(2012)03- 但41 -03 摘 要 对常用的 4 种抗病血压药厄贝沙坦、依那普利、美托洛尔拉籍、-l.氯地乎进行成本·效果分析。方法:选择2(阴年 1 月一 2011 年 1 月我院门诊高血压患者 320 i列为研究对象，并按随机抽样原则分为 4 组，分!I J .Il.周 4 种抗高血压药，疗程 12 周，根据疗 效进行成本·效果分析。结果:厄贝沙坦、依那普利、.l.氯地乎纽疗效优于美托洛尔组 (P 0. 05); 成本·效果分析，费用效果比最优 为尼贝沙坦组。结论:药物经济学在为高血压患者合理选药、为患者提高依从性和拉伽I.ì!标牟、显著改善患者的生存质量、有效降 低疾病负担等方面具有重要意义。 关键词 *发性高血压;抗高血压药;药物经济学;成本·效果分析 Cost-etTectiven倒 Analysis of Four Commonly Used Antihypertensive Drugs for Essential Hypertension TAN Ye-hui. , HUANG Qi-liang (Foshan Nanhai District Guicheng Hospital , Guangdong Foshan 5282∞， China) ABSTRACT OBJECηVE: To conduct cosl-effecliveness analysis for four commonly used anlihypertensive drugs (Irbesartan , Enalapril , Metoprolol controlled release tablet , Amlodipine). METHODS: 320 palienls with prim且可 hypertension in our hospital enrolled between January 21创沟 and January 2011 were assigned to receive one of Ihe four antihypertensive drugs-I由e刨出n ， Enalapril , Metoprolol controlled release tablel or Amlodipine for 12 weeks. Based on 由e curalive efficacy , a cost-effectiveness analysis was performed. RESULTS: Irbesartan , Enalapril and Amlodipine were superior to Metoprolol conlrolled rele脱 tablel (P O. 05). In terms of cosl-effecliveness , 1 由esa血n was the best one among the 4 drugs. CONCLUSION: Pharmacoeconomics is of great importance for hypertensive patients in rational choice of drugs , and it can help increase patients compliance and target-meeting ra怡。f patients remarkably improve patients qualify of life and effectively reduce patien钮， burden of di 能ase. KEY WORDS Essentia1 hypertension; Antihypertensive drugs; Pharmac侃conomics; Cost-effecliveness analysis 高血压是一种以动脉血压持续升高为主要表现的心脑血 付出的