PowerPoint 演示文稿 - bio.med.stu.edu.cn.ppt

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PowerPoint 演示文稿 - bio.med.stu.edu.cn.ppt

Vitamins and Microelements Introduction Definition organic substances , essential in the diet in small amounts that are involved in fundamental functions of the body Section I??????? Lipid-soluble Vitamins Common features ﹡nonpolar (hydrophobic) isoprene derivative ﹡poorly soluble in water,but good in fat and fat solvents ﹡existing with the lipids in food products and absorbing with the lipids ﹡ specifically binding to lipoprotein and certain binding-protein in blood and transportation Classification: VitA, VitD, VitE, VitK Vitamin A Synthesis and decomposition of Rhodopsin and relation to retinal Vitamin E (Tocopherol) biochemical function and deficiency anti-oxidation Vitamin E: antioxidant ROO· ? RH ? ROOH ? R· (Peroxide free radical ) (polyunsaturated fatty acids )(organic peroxide )(organic free radical) R· ? O2 ? ROO· ROO·+Vit E-OH?ROOH?Vit E-O· Maintaining reproduction Promoting metabolism of Hb (?- amino-?- levulinate synthase ALA) Section Ⅱ Water-soluble Vitamins The Process of Aerobic Oxidation of Carbohydrates (一)oxidative decarboxylation of pyruvate Vitamin B2 (riboflavin) FMN: 6、7-dimethyl-isoalloxazine ribotol FAD 6、7-dimethyl-isoalloxazine adenine ribotol ribose Phosphoric acid Phosphoric acid Vitamin B3 (nicotin acid, nicotinamid, Vitamin PP) NAD+ and NADP+ nicotinamide adenine ribose ribose-( Phosphoric aci

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