第9-2章微生物学(赵立平).pdf

Virus: Growth, quantification, replication and diversity Lecture 9-2 Essentials of Virology CHAPTER 10 in BROCK BIOLOGY OF MICROORGANISMS School of Life Science and Biotechnology, Shanghai Jiao Tong University Shanghai Jiao Tong University III. Viral Replication 9.4 General Features of Virus Replication 9.5 Virus Multiplication: Attachment and Penetration 9.6 Virus Multiplication: Production of Viral Nucleic Acid and Protein 9.7 Virus Multiplication: assembly and release Shanghai Jiao Tong University Shanghai Jiao Tong University 9.6 Virus Multiplication: Production of Virual Nucleic Acid and Protein Viruses have different types of genomes, including double-stranded/ single-stranded DNA and double- stranded/ single-stranded RNA. Shanghai Jiao Tong University Shanghai Jiao Tong University The Baltimore Classification system of viruses Class I Double-stranded DNA genome Class II Single-stranded DNA genome Class III Double-stranded RNA genome Class IV Single-stranded RNA genome of plus sense Class V Single-stranded RNA genome of minus sense Class VI Single-stranded RNA genome that replicates with DNA intermediate Class VII Double-stranded DNA genome that replicates with RNA intermediate Shanghai Jiao Tong University Shanghai Jiao Tong University Configuration of nucleic acid sequences 核酸序列的构型 Shanghai Jiao Tong University Formation of mRNA after infection of cells by viruses of different types dsDNA virus (class I): production of ssDNA virus (cla