心可舒对冠心病合并2型糖尿病患者.PDF

·301· ．1J告床研究· 心可舒对冠心病合并2型糖尿病患者 NO、ET的影响 丁俊蓉许华强周益伟任静 【摘要】 目的观察心可舒胶囊对冠心病合并2犁糖尿病患者血浆一氧化氮(NO)、内皮素(ET)水平的影响， 探讨心可舒胶囊的治疗作用。方法符合入选标准的80例患者随机分为两组，每组各40例。治疗3个月后，比较患 者血浆NO、ET水平的变化。结果治疗组NO明显升高，且高于对照组(P0．01)：ET明显降低，且低于对照组 (P0．01)。结论心可舒胶囊可能通过升高NO、降低ET发挥保护血管内皮作用。 【关键词】 心可舒胶囊；冠心病合并2型糖尿病；一氧化氮：内皮素 InfluenceofXin．ke．shu onN0andETinPatientswith Diseaseand Capsule CoronaryArtery 2DiabetesMellitus Internal DiNG Yi—wei,REN of 日pe Jun．rong‘．XUHua．qiang．zHoU Jing．Department Health Medicine。Motherand劭fld of 261011。China HospitalWeifang，腑妇ng Toobservethe of andETin with influenceXin—ke—shu NO 【Abstract]0bjective Capsule(XKsc)onPatients disease【CAD)combinedwitIltype2diabetesmeuitus(T2DM)，andto itsmechanismof coronaryartery invesfigam treatment．Metitods80 wi山CADcombinedwitllT2DMwere recruitedintOtwo inthe patients ralldomly groups：40patienIS treatmentweretreatedconventional XKSC．andthe40inthecontrDl treatedconventional group by therapyplus group by levelofNOandETwasobservedbeforeandafterthethree—mortth course． tllerapyexclusively．Theplasma therapeutic iIl ResultsThe levelofETint11etreatment decreasedafterthetreatmentandwaslowerthallthat plasma groupsignificantly thecontrol N0int11etreatmentelevated andWas thanthatinthecontrol group(P0．01)．but group sig