胃癌患者术前CRPAlb比与淋巴结转移相关性的研究.PDF

210 中国肿瘤临床2017年第44卷第5期 ChinJClinOncol2017.Vol.44.No.5 临床研究与应用 · · 胃癌患者术前CRP/Alb比与淋巴结转移相关性的研究 乔乐乐 王公平 周博 金灿辉 汪增方 杨言通 智鹏柯 陈晔 解延飞 冯笑山 摘要 目的：探讨胃癌患者术前CRP/Alb比（CAR）与淋巴结转移的关系。方法：选取2013年10月至2016年9月河南科技大学第 一附属医院收治的96例胃癌患者，以术前CAR为因变量对胃癌患者临床病理分期及术中淋巴结检出情况进行分析。结果：1）术 前CAR≤0.04与CAR0.04的患者比较，后者有更高的转移率和转移度，且差异有统计学意义（P0.05）。术前CAR0.04组的患者 中，淋巴结分期N0者明显多于术前CAR≤0.04组，且差异有统计学意义（P0.05）。2）Borrmann分型Ⅰ、Ⅱ、Ⅲ、Ⅳ型患者的CAR 均逐渐增高；随着胃癌病理分期的进展，CAR均值增高。3）术中淋巴结清扫总数较多组，其术前CAR均值偏高。结论：胃癌患者 术前CAR的高低与淋巴结转移之间具有相关性，可以在一定程度上反映淋巴结转移的程度。 关键词 胃癌 CRP/Alb比（CAR） 淋巴结转移 doi:10.3969/j.issn.1000-8179.2017.05.246 Correlation between preoperative CRP/Alb ratio and lymph node metastasis in pa- tients with gastric cancer Lele QIAO, Gongping WANG, Bo ZHOU, Canhui JIN, Zengfang WANG, Yantong YANG, Pengke ZHI, Ye CHEN, Yanfei XIE, Xiaoshan FENG Correspondence to: Xiaoshan FENG; E-mail: samfeng137@ Department of Gastrointestinal Tumor Surgery, The First Affiliated Hospital and College of Clinical Medicine of Henan University of Sci- ence and Technology, Luoyang 471003, China Abstract Objective: To investigate the relationship between Creactive protein(CRP)/albumin ratio (CAR) and lymph node metastasis of gastric cancer. Methods: A total of 96 cases of gastric cancer were included in the study. The clinical pathological stage and lymph node detection in patients with gastric cancer were analyzed, with the preoperative CAR as the dependent variable. Results: 1) The pa- tients with preoperative CAR 0.04 has higher transfer rate and metastasis than the patients with preoperative CAR ≤0.04, and the dif- ference was significant (P0.05). The lymph node stage of patients with preoperative CAR 0.04 was significantly higher than that of the patients with preoperative CAR ≤0.04, and the difference was significant (P0.05). 2) The mean CAR of patients with Borrmann types Ⅰ, Ⅱ, Ⅲ, and Ⅳgradually increased; with the progression