Diane -35 Metformin treatment of PCOS with infertility clinical analysis of 62 cases.doc

Diane -35 Metformin treatment of PCOS with infertility clinical analysis of 62 cases [Abstract] Objective To observe Diane -35 Metformin for polycystic ovary syndrome (PCOS patients with reproductive hormones and ovulation rate and pregnancy rate. Methods 62 cases of infertile women with PCOS were randomly divided into three groups. A group diet , B metformin alone group, C group took up British -35 Metformin, B, C group were taking three consecutive months, the three groups after 3 months with clomiphene citrate (CC) ovulation induction. reproductive hormones before and after treatment level changes and ovulation rate and pregnancy rate. Results After treatment, the serum C LH, T, LH / FSH, IN drop, compared with before treatment was significant difference (P all lt;0.01.C group ovulation rate and pregnancy rates were 77.59%, 32.75%, B group were 52.83%, 13.21%, A group were 38.18%, 3.63%, C group was higher than A, B group (P lt;0.01 or P lt;0.05. Conclusions of the British - Metformin treatment of PCOS 35 can significantly improve the endocrine environment, improve ovulation and pregnancy rates of patients. [Keywords:] Polycystic Ovary Syndrome / women of the British treatment of infertility metformin -35 Polycystic ovary syndrome (polycystic ovarian syndrome, PCOS) is hyperandrogenism (HA), insulin resistance (IR, hyperinsulinemia and anovulation, characterized by long-term gynecological common endocrine metabolic diseases, the incidence of women of childbearing age rate of 5% to 10%, accounting for anovulatory infertile women, 75% [1]. of the British -35 PCOS patients can reduce the clinical symptoms, improve endocrine disorders. However, oral contraceptives may aggravate PCOS women, IR, PCOS does not improve or increase the metabolic syndrome associated with abnormal lipid status [2]. metformin by increasing peripheral tissue glucose utilization, accelerated anaerobic glycolysis, gluconeogenesis glycogen decrease, inhibit or slow down the intestinal g