噻二唑基_3_2H_哒嗪酮类化合物的合成及生物活性_曹松.pdfVIP

2004, 6(2) : 6871 Chinese Journal of Pesticide Science 研究简报 -3( 2H ) - * 曹　松, 　曲玉成, 　宋恭华 , 　钱旭红, 　黄青春, 　卢德力 ( , ( ) , 200237) :, 2 5 1, 3, 4 , 2 4 5 3 1 ( 2H ) , 8 , H NMR , . . , P sep arate W 3b EC 21 mg/ L 50 : ; ; ; :T Q453. 6: A : 1008 7303( 2004) 02 0068 04 3( 2 ) - Synthesis and Biological Activities of New Thiadiazolyl H pyridazi nones * CAO Song, QU Yu cheng, SONG Gong hua , QIAN Xu hong, HUANG Qing chun, LU De li ( Institute of Pesticides and Pharmaceutical, East China University of Science and Technology, . . 544, 130 , 200237, ) P O Box eilong Road Shanghai China Abstract: Eight new thiadiazolyl 3 ( 2H ) pyridazinones compounds were synthesized by the reaction of 2 tert butyl 4 chloro 5 hydroxy 3 ( 2H ) pyridazinones with 5 aryl 2 chloromethyl 1, 3, 4 . oxadiazoles which were prepared by the cyclization of N chloroacetyl N aroylhydrazines 1 The structure of the title compounds were confirmed by H NMR HR mass spectra and elemen, tal analysis T heir biological activities were examined and some of them exhibited good activities. 50