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用分水岭算法计算髓鞘厚度的生物学分析.pdf
Calculating Myelin Sheath Thickness with Watershed
Algorithm for Biological Analysis
By
Kenneth Huang (1), Yunxia Ji (2), Steed Huang (2) and Qi Chen (3
1 Thurgood Marshall College, UC San Diego,
9500 Gilman Dr. La Jolla, CA 92093, USA
2 Suqian College, Jiangsu University, 399 South
Huanghe, Jiangsu 223800, P.R. China,
3 Shanghai Institute of Technology, 100 Haiquan
Road, Shanghai 201418, P.R. China,
Agenda
1. Introduction
2. The Image Based Biological Analysis
3. Watershed Algorithm
4. Matlab Program
5. Summary
1. Introduction
The initial analysis does indicate that the mixed
method we adopt improved efficiency of data
processing, while not overlooking some important
medical diagnostics factors:
Significance of the myelin thickness (g-ratio) to
various root courses of the diseases for human
being
Similarity between the human and the lab
mouse
The amount of fat accumulation will affect the
brain cell
Myelin is a unique way to increase conduction
speeds and strength along axons of relatively
small calibers.
About Sphingomyelin
25% of fatty acids including sphingomyelin in a human being are:
inside the brain; however, the weight of the brain is only 2% of the entire body.
The majority of the fat is inside the neuron, consisting of the myelin sheath that
insulates the axon of the neuron while providing the supporting structure to the
entire brain at the same time.
As such, checking the myelin thickness (g-ratio) of the axon must have some
medical significance related to some, if not all aging diseases.
• It is known that a number of human diseases, such as Alzheimer, dem
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