《肝纤维化中西医结合诊疗指南》(国外英文资料).doc

《肝纤维化中西医结合诊疗指南》 The organization is an expert in the organization, since 2003, it has been discussed and revised several times, and it has been written for reference. The evidence for recommendations in the body is divided into three levels of five grades (table 1), which is represented by the Roman numeral in brackets. Table 1 provides evidence of the recommendation The amount classification Class definition of evidence Ⅰ randomized controlled clinical trials Ⅱ - 1 controlled but not randomized clinical trials Ⅱ - 2 cohort or case-control study Ⅱ - 3 time more cases series analysis, the results obviously not controlled trials Ⅲ expert opinion and descriptive epidemiological studies A, diagnosis, (1) clinical manifestations The clinical manifestations of liver fibrosis were non-specific and significant. Common clinical manifestations are: abnormal tired weakness, loss of appetite, stool, liver area unwell or swelling or pain, dim complexion, dark red tongue, fine sublingual veins, arteries and veins, etc. Some patients may not have obvious symptoms and signs, or may be present in other clinical manifestations of the disease. (2) pathology, laboratory and imaging examination Histopathologic examination: histopathologic examination is the most important basis for determining the degree of inflammation and fibrosis, as well as determining the efficacy of drugs. The basic requirements of liver biopsy include: the aim of using a needle piercing (16G), with a length of more than 1cm, at least six or more. The liver biopsy specimen should be continuously sliced, and the routine is a cyana-ired, Masson dyeing and (or) reticular fiber dyeing. According to the degree of fibrosis, the degree of liver fibrosis is divided into l ~ 4 stages. You can also refer to the scale of the liver fibrosis by referring to Knodell, Ishak, Scheuer, Chevallier, etc. [5-8]. Table 2 levels of inflammatory activity of livers and levels of fibrosis Degree of inflammation activity degree Degree of f