手术放大镜下行翼状胬肉切除联合自体角膜缘干细胞移植术临床分析.doc

手术放大镜下行翼状胬肉切除联合自体角膜缘干细胞移植术临床分析 　　作者：严吕霞,严锦云　　作者单位：中国湖北省仙桃市第一人民医院眼科 　　【摘要】目的：观察手术放大镜下行翼状胬肉切除联合自体角膜缘干细胞移植治疗翼状胬肉的临床疗效。方法：对102例104眼原发性翼状胬肉患者在手术放大镜下行翼状胬肉切除联合自体角膜缘干细胞移植，观察术后复发情况。结果：术后随访3～12mo，6眼复发，复发率为5.8%。结论：手术放大镜下行翼状胬肉切除联合自体角膜缘干细胞移植治疗原发性翼状胬肉，能有效降低胬肉术后复发率，是目前医疗条件下值得推广的手术方法。 　　【关键词】 手术放大镜;原发性翼状胬肉;角膜缘干细胞;移植术 　　Clinical analysis of pterygium excision combined with autologous limbal stem cell transplantation under microscope 　　L?Xia Yan, JinYun Yan 　　Department of Ophthalmology, the First Peoples Hospital of Xiantao, Xiantao 433000, Hubei Province, China 　　Correspondence to: L?Xia Yan. Department of Ophthalmology, the First Peoples Hospital of Xiantao, Xiantao 433000, Hubei Province, China. lincon@ 　　Received:20100719 Accepted:20100811 　　Abstract 　　AIM: To observe clinical effect of pterygium excision combined with autologous limbal stem cell transplantation under microscope. 　　METHODS: Totally 102 patients 104 eyes with primary pterygium underwent pterygium excision combined with autologous limbal stem cell transplantation by microscope and the postoperative recurrence rate was observed. 　　RESULTS: All patients were followed up from 3 to 12 months. 6 cases recurred after surgery, and the recurrence rate was 5.8%. 　　CONCLUSION: Pterygium excision combined with autologous limbal stem cell transplantation under microscope can reduce the recurrence rate of primary pterygium,and is a surgical method worth extending in primary hospital. 　　KEYWORDS:surgical microscope; primary pterygium; corneal limbal stem cells; transplantation 　　Yan LX, Yan JY. Clinical analysis of pterygium excision combined with autologous limbal stem cell transplantation under microscope. Int 　　J Ophthalmol (Guoji Yanke Zazhi) 2010;10(9):18211822 　　翼状胬肉是眼科的常见病和多发病,治疗方法以手术为主,按常规方法治疗，复发率仍很高,国内报道20%～70%,国外报道24%～89%[1],随着显微手术的发展，手术方法的改进以及抗结缔组织增殖药物的应用，使该手术的复发率日渐降低。我院自200703/200903在门诊使用手术放大镜下行胬肉切除联合自体角膜缘干细胞移植术治疗原发性翼状胬肉102例104眼，收到明显效果