化学消毒剂作用机理研究进展-吴清平.pdf

2006 33 ( 6) # 117# 1 1, 2, 3 1, 3 4 吴清平 韦明肯 吴军林 阙绍辉 ( 510070) 1 2 3 ( 537000) ( 510301) ( 510070) 4 : , , , : , , , , : Q93 : A : 0253-2654 ( 2006) 06-0117-05 Advance in ActionM ode of Chem icalD isinfectants 1 1, 2, 3 1, 3 4 WU Q i g-Pi g WE IM i g-Ke WU Ju -L i QUE Shao-Hui (Guangdong Institute of M icrobioloy, Guangzhou 510070) 1 (Guangx i Yulin Normal College, Yulin 537000)2 (South China Sea Institute of Oceanology, Guangzhou510301)3 (Guangdong uankaiM icrobiologicalScience and Technology Co1 Ltd, Guangzhou 510070)4 Abstract: Cellmembra es play a mi porta t role i resista ce ofm icroorga ism s to chemical disi fecta ts1 The effects of disi fecta ts o cell membra es i clude the alteratio of permeability, leakage of i tracellular sub- sta ces, damagi g the respiratio chai s a d so o 1 Though the structures a d fu ctio s of protei s a d DNA a-l tered by some disi fecta ts, the sy thetical processes of them seemed to be more se sitive1 F low cytometry ( FCM ) a d si g le-cell gel electrophoresis ( SCGE) are prom isi g tech ology which should be efit the i vestiga- tio of actio mode of chemical disi fecta ts1 K ey words: Chem ical disi fecta ts, Actio mode, Cellmembra e, Protei, Nucleic acid , , , , , 1 , Tel: 020(,