抗菌药物专项整治期间我院住院患儿抗菌药物应用分析.pdf

抗菌药物专项整治期间我院住院患儿抗菌药物应用分析 ＊ # 马新燕 ，何新苗 ，刘 洁（乌鲁木齐市第一人民医院/ 乌鲁木齐儿童医院，乌鲁木齐 830002） 中图分类号 R978.1；R969.3 文献标志码 A 文章编号 1001-0408（2015）26-3628-04 DOI 10.6039/j.issn.1001-0408.2015.26.08 摘 要 目的：为促进抗菌药物合理使用和规范化管理提供参考。方法：从医院信息系统提取我院开展抗菌药物专项整治活动的 2011－2014年住院患儿使用抗菌药物相关信息，对抗菌药物使用相关数据进行统计分析，考察我院住院患者抗菌药物使用率、使 用金额、用药频度（DDDs ）、Ⅰ类切口手术抗菌药物预防使用率等指标的变化。结果：2011－2014年我院住院患儿抗菌药物使用 金额在药品总额的占比呈下降趋势；抗菌药物使用率和Ⅰ类切口手术抗菌药物预防使用率显著降低，分别由2011年的77.30％和 47.57％下降至2014年的57.24％和5.89％；头孢吡肟使用金额连续3年位居前3位，头孢噻肟、头孢哌酮/舒巴坦DDDs 连续4年位 居前2位。结论：抗菌药物专项整治活动的开展在我院取得了明显成效，住院患儿抗菌药物各项用药指标得到明显改善，抗菌药 物临床应用日趋合理，为抗菌药物临床应用与管理的持续改进奠定了良好基础。 关键词 住院患者；抗菌药物；用药频度；用药分析；儿童用药 Analysis of the Utilization of Antibiotics in the Inpatients of Our Hospital during Special Rectification MA Xin-yan ，HE Xin-miao ，LIU Jie （Urumqi First People ’s Hospital Urumqi Children ’s Hospital ，Urumqi 830002， China ） ABSTRACT OBJECTIVE ：To provide reference for rational use and standard management of antibiotics. METHODS ：The relevant information for antibiotics used in the inpatients of our hospital involved in antibiotics special rectification during 2011 to 2014 were extracted from hospital information system ，and the relevant data of antibiotics use were analyzed statistically. The changes of several indicators in the inpatients of our hospital were investigated ，including the utilization rate and amount of antibiotics ，DDDs and the uti- lization rate of type Ⅰincision antibiotics for prophylactic use. RESULTS ：The ratio of consumption sum of antibiotics in total con- sumption sum were decreasing from 2011to 2014. The utilization rate of antibiotics and of type Ⅰincision antibiotics for prophylactic use were decreased significantly ，decreasing from 77.30％and 47.57％in 2011to 57.24％and 5.89％in 2014. The consumption sum of cefepime occupied the first 3 places in 3 years. DDDs of cefotaxime and cefoperazone/sulbactam occupied the first 2 place