智能化和精确化用药监测软件的研发及应用.pdf

·医院药学 · 智能化和精确化用药监测软件的研发及应用 1 2* 朱珺 (1.上海同济大学附属东方医院，上海 200120 ；2.上海交通大学附属胸科医院，上海 200030) 摘要：目的 方法 CPM- 3 14 2 12 CPM- 2 结果 38 2.7% 2 89 1.43% 27 0.36%13 1.1%结论 CPM- 关键词：CPM- 中图分类号：R9-39 文献标志码：B 文章编号：1007-7693(2010)04-0361-05 The Effect of Developing the Intelligent and Accurate Software of Monitoring on Drug Use 1 2* ZHAI Xiaobo , ZHU Jun (1.Affiliated Dongfang Hospital, Tongji University, Shanghai 200120, China; 2.Shanghai Chest Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200030, China) ABSTRACT: OBJECTIVE To develop the intelligent and accurate software of monitoring on drug use in order to decrease the harmfulness of preventable adverse drug events. METHODS To develop the “antibacterial-application software” successfully basing on pharmacokinetics and pharmacodynamics of antibiotics. To develop “the intelligent prescription screening system” successfully and realize the connection between “contraindications” with diagnosis of patients, their laboratory results basing on the information system of the hospital. Selected the respiratory medicine of a hospital as the experiment group, and the respiratory medicine of the other three hospitals as the contrast group. During the former 14 months, both groups were not intervened. During the latter 12 months, in the experimental group, using “the intelligent prescription screening system” and “antibacterial-application software” to examine prescriptions and returned the “contraindications” or antibacterial dose errors to the doctors and gave the relative education. There were no interventions in the contrast group. In addition, all adverse drug events of t