71例头孢曲松钠致过敏性休克的分析.pdfVIP

71 1 1 2 陈亚媚 , 郦尧旺, 朱光辉 ( 1. , 312000; 2. , 325027) : 分析头孢曲松钠致过敏性休克的发生特点及相关因 , 为临床合理使用头孢曲松钠提供参考 对国内近 14年来发表的 71例头孢曲松钠致过敏性休克病例进行回顾性分析 头孢曲松钠可致过敏性休克, 严重的过敏性休克 可致患者死亡 严格用药指征,用药前详细询问过敏史, 特别是患者的基础性疾病; 加强药物不良反应监测, 促进临床 合理用药, 严防死亡病例发生 : 头孢曲松钠; 药物不良反应;过敏性休克; 死亡 : R994. 11 : B : 2009) Analysis of71 Caseswith Allergic Shock Induced by Ceftriaxone Sodium HEN Yame,i LIY aowang, ZHU Guanghui ( 1. Shaox ing H osp ital of T rad it ional Ch inese M ed ic ine, Shaox ing 312000, Ch ina; 2. The Second Aff iliated H osp ital of Wenzhou M ed ical Co lleg e, W enzhou 325027, Ch ina ) ABSTRACT: BJECTIVE To analyze the characteristics and relative factors of allergic shock induced by ceftriaxone sodium, in order to provide reference for the clinical use of ceftriaxone sodium properly. METH DS The 71 reported cases of allergic shock induced by ceftriaxone sodium in hina over 14 years w ere retrospectively analyzed. RESULTS eftriaxone sodium could induce allergic shock, and the severe case could cause death. C NCLUSI N W e should control the drug indication strictly, check patients drug allergy history carefully before prescription, especially patients associated w ith basic diseases, monitor adverse drug reaction ( ADR) afterw ards, promote clinical rational drugusage, and prevent death. KEY W RDS: ceftriaxone sodium; adverse drug reactions; anaphylactic shock; death , 2. 1 , , 7~ 8 h, 71, 37 ( 52. 1% ) 33 1; ( 46. 5% ), 1( 1. 4% ) 1~ 96 , , ! 20 14 ( 19. 7% ), 21~ 40 30 , (ADR) ( 42. 3% ), 41~ 60 16( 22. 5% ), 60 11 , , , ( 15. 5% ) 2. 2 71, 38( 53. 5% ), 1 22 ( 31. 0% ), 6