Blackwell Publishing, Inc. C ○ 2005 International League Against Epilepsy Computerized Mot.pdf

Epilepsia, 46(6):901–917, 2005 Blackwell Publishing, Inc. C 2005 International League Against Epilepsy Computerized Motion Analysis of Videotaped Neonatal Seizures of Epileptic Origin ∗Nicolaos B. Karayiannis, ∗Guozhi Tao, ∗Yaohua Xiong, ∗Abdul Sami, ∗Bindu Varughese, †James D. Frost, Jr., †‡Merrill S. Wise, and †‡Eli M. Mizrahi ∗Department of Electrical and Computer Engineering, University of Houston; †Peter Kellaway Section of Neurophysiology, Department of Neurology; and ‡Department of Pediatrics, Baylor College of Medicine, Houston, Texas, U.S.A. Summary: Purpose: The main objective of this research is the (80 cases). The outcome of the experiments verified that optical- development of automated video processing and analysis proce- flow methods are promising computational tools for quantifying dures aimed at the recognition and characterization of the types neonatal seizures from video recordings in the form of motion- of neonatal seizures. The long-term goal of this research is the strength signals. The experimental results also verified that the integration of these computational procedures into the develop- robust motion trackers developed in this study outperformed con- ment of a stand-alone automated system that could be used as siderably the motion trackers based on predictive block matching a supplement in the neonatal intensive care unit (NICU) to pro- in terms of both reliability and accuracy. The quantitative fea- vide 24-h per day noninvasive monitoring of infants at risk for tures selected from motion-strength and motor-activity signals seizures. constitute a satisfactory representation of neonatal seizures and Methods: We developed and