非淋菌性泌尿生殖道炎支原体感染及耐药变迁.pdfVIP

234 Chinese Joumal of Microecology ,June 2∞6 ,Vol. 18 No. 3 文章编号:1ω5-376X(2(刷)03 .Q234 .Q2 [ I恼廊研究] 非淋菌性泌尿生殖道炎支原体感染及耐药变迁 徐缸云，刘森林，薛云松，李红 (云云南省第二人民医院检输科，云南昆明 650021) {摘盛] 目的 探讨解腺文服体(Uu) 及人型文原体(Mh) 在非淋菌性泌原生殖道炎的感染状况，分析近3 年 来支原体的感染及耐药变迁。方法采用培养法(Mycoplωma 1ST) 对 NGGU 的分邮物进行文原体的培养、体外商 敏试验及分析。结果 支原体阳性率为47.0% ，其中 Uu 阳性率为34.09岛， Uu +Mh 阳性率为 1 1. 4% ， Mh 阳性率为 1. 6%;交沙每索、强力霉紫等药物的敏感率先明显变化，而唾诺酬类的耐药率则盟逝渐上升趋势，环两沙星及氧氟 沙攘的耐药率分别从2ω2 年的 38.9% 及40.0% 上升到了2{泊4 年的79.2% 及66.4% 0 结论文原体的耐荷率正 逐步增加，其中喳诺酣类的高耐药率提示其在治疗支原体感染中的地位改变，泌尿~殖道支原体的药物敏感监测 对临床治疗具有重要善意义。 [关键词] ~非淋菌泌尿~殖遇炎;文原体感染;耐葫变迁 [中图分类号]阳75 [文献标识码]A Infec筒。，nand 由旧~ susceptibility 倒也 01 1\今Icop1asnωin nongon刚刚冶1 geniωurethri也 XU Hong-yun ,UU Chun-lin ,XUE Yur卜song ， U Hong ( The Second U叩ital of Yunna冉冉OVince ,Kunming 65∞12 ， China) [ Abstract] Objective To study infonnation about inf酬。n and drug resistance chara l伊严i让cuω肌w刷m (Uu加u) 皿d A(今伽y严cωoψp缸阳S1阳n阳zωα h阳om川in川is (Mh川).Me幽仙ods Myco叩pl阳a翩sma 览1ST kit饱sw附ere uω吕e叫d tωo cu山ù山ltu脚1I阴re哇 My.ω叩pla阳sm阳a 汕in no佣n俐 gono盯啊c州alg阱e衍eni时út阳o例刷u且lre附削咽悦thritis patien协 with secretion and to analyze the drugs sus侃ptibility for three years. Results Among 711 cases ,mycoplasrna positive rate was 47. 0% ,Uu p佣itive rate was 34. 0% ,Uu + Mh positive rate was 11. 4% ,Mh posi- tive rate wω 1. 6% ;The result of susceptibility showed that the tendency of drug resistance was 萨。明ng ye缸 by year. 叽忧 。iprofoxacin and of1oxacin showed a high resistance rate. Josamycin and doxycyclin were sensitive 剧tibi州帆 ConclusioDS The drug resistance of mycoplasma w臼 increasing with time. 饥le ciprofoxacin and of1oxacin was not rnain drugs for myco- plasma. Drug resistance test could be used to supervise the treatment and to give d