我国奶牛乳房炎常见病原菌的耐药性检测_王正兵.pdfVIP

　　20 11, 39 (4 ):139 ～ 141 　G uizho u A g ricultural Science s []100 1-360 1(20 11)04-0248-0139-03 我国奶牛乳房炎常见病原菌的耐药性检测 1 2 2 2 1 2 ＊ 2 2 王正兵, 严作廷 , 罗金印, 李新圃, 贾 宁, 李宏胜 , 王玲, 苗小楼 (1., 730070;2. , 730050) 　　[　] 为了解我国奶牛乳房炎主要病原菌对常见抗生素的耐药情况,以指导临床 理用药, 从奶牛 场采集的临床型乳房炎病乳中分离鉴定出无乳链球菌、停乳链球菌、金黄色葡萄球菌和大肠杆菌, 每种菌20 株,采用药敏纸片法进行常见抗生素的耐药性检测。结果表明, 大部分抗生素对奶牛乳房炎的4 种主要菌均 产生了不同程度的耐药性,其耐药率达10 %～100%,未发现1 种对4 种菌均高度敏感的药物。对4 种菌均 有抑制作用的药物有氟苯尼考、左氟沙星、洛美沙星、氟哌酸和头孢类药物,其敏感度达60%～100 %;对4 种菌产生较强耐药性的药物主要有青霉素G 、链霉素和复方新诺明, 其耐药率达 30%～100%。试验结果对 进一步监测奶牛乳房炎主要病原菌的耐药变迁情况,指导临床 理用药具有重要的意义。 [] 奶牛乳房炎;病原菌;抗生素;敏感性 [] S823.9+1 [] A Drug Resistance of Common Pathogenic Bacteria in Subclinical Mast it is in China 1 2 2 2 1 WA NG Z heng-bing , YA N Zuo-ting , L UO Jin-yin , L Xin-pu , J A Ning , 2 ＊ 2 2 L H o ng-sheng , WA NG Ling , M A O Xiao-lou (1.Gans u Ag ricultural University , Lanz hou, Gansu 73 0070;2.Lanzhou A nimal H usb andry and Veterinary I ns titute, CAAS, L anz hou, Gans u 730050, China) 　　Abstract:T o know antibiot ic susceptibility of m ain pathog ens in subclinical mastiti s and g uide clinical drug use reasonably , A ntimicrobial susceptibility tests of S .ag al actiae, S .dy sg a lacti ae, S .aureus and E .co l i, which we re i solat ed f rom milk samples of dairy cow w it h clinical mastitis, w ere perfo rmed using slip method .T he result s showed that the fo ur pathog ens w ere resistant to antibiotics in varying deg rees with resi st ance rate ranging f ro m 10 %t o 100%.No antibiotic w as f ound with high suscept ibility to the fo ur pa thogens.T h