小儿支气管哮喘疾病与肺炎支原体感染相关性研究.doc

小儿支气管哮喘疾病与肺炎支原体感染相关性研究 摘要：本研究选取2010-2015年期间200例在我院小儿内科确诊为由于肺炎支原体感染导致支气管哮喘的患者，对照组为90例非肺炎支原体感染的支气管哮喘小儿患者。以此来分析两组患者的临床特点、喘息症状以及药物治疗过程中的反应情况。结果发现小儿支气管哮喘与肺炎支原体感染存在明显相关性的年龄多发生在2-7岁之间，平均年龄4.1岁，并且哮喘与支原体被感染的次数相关；另外，实验组与对照组患者在喘息特点、发热情况以及哮喘时长对支气管扩张剂的反应等方面与对照组存在统计学上的显著差异；肺炎为主要诱导因素促使呼吸系统支原体感染，且发现平喘药联合阿奇霉素对于治疗有肺炎支原体感染诱发的哮喘疗效较好。关键词：支气管哮喘；小儿；肺炎；支原体感染This study selected 200 cases during 2010-2015 in our hospital diagnosed pediatric medicine due to Mycoplasma pneumoniae infections in patients with bronchial asthma, the control group of 90 patients with non-asthmatic pediatric patients with Mycoplasma pneumoniae infection. In order to analyze the clinical characteristics of the two groups of patients, wheezing and drug reactions during treatment. The results showed that children with bronchial asthma and Mycoplasma pneumoniae infection significant correlation between age occurred in 2-7 years, the average age of 4.1 years old, and the number of asthma associated with Mycoplasma infected; in addition, the experimental group and the control group of patients wheezing characterized by the presence of aspects, as well as the heat of the bronchodilator response to long-time asthma control group statistically significant difference; pneumonia as the main factors have contributed to induce respiratory infection, and found that asthma drugs in combination with azithromycin for the treatment of mycoplasma pneumoniae infection better efficacy induced asthma. Keywords: Bronchial asthma; Children; Pneumonia; Mycoplasma 前言 哮喘病发与呼吸道感染非常紧密，特别是病毒感染引起的呼吸道病变。其中，鼻病毒和合胞病毒是引起哮喘的最主要诱因。近些年来，随着小儿支气管哮喘和肺炎支原体感染病例的逐渐增多，国内外关于二者的联系也越来越予以重视。呼吸道感染病原除了细菌和病毒外，支原体是最为主要的因素，并且研究发现小儿哮喘与肺炎支原体感染密切相关[1-4]。研究发现，小儿哮喘的发病率近年来有不断上升趋势[5-9]，已经严重影响到了儿童的健康成长。据此，本文就小儿哮喘和肺炎支原体感染的相关性就行了分析，以期对该疾病的诊断和治疗提供参考。 材料和方法 临床资料 根据我院2010-2015年儿科确诊记录，共发现有200例患者是由于肺炎支原体感染引发的小儿哮喘，将其设为实验组，男女比例为1.8:1；年龄2-7岁，平均4.1岁。其中2-3岁81例，4-6岁85例，6-7岁34例。本研究所参考的对照组为90例非支原体感染的同期诊断为哮喘的小儿，包括男孩58例，女孩32例，均龄4.6岁。实验组和对照组儿童的年龄、性别均无统计学上的差异（P0.05），具有显著可比性。 诊断标准 以儿科学（诸福棠）小儿支气管哮