Lecture8Olefin Addition Reactions–1.pdf

D. A. Evans Olefin Addition Reactions: Part–1 Chem 206 Other Reading Material /~chem206/ Smith, K. and A. Pelter (1991). Hydroboration of C=C and Alkynes. Comprehensive Organic Synthesis. B. M. Trost and I. Fleming. Chemistry 206 Oxford, Pergamon Press. 8: 703. Beletskaya, I. and A. Pelter (1997). “Hydroborations catalysed by Advanced Organic Chemistry transition metal complexes.” Tetrahedron 53(14): 4957-5026. Brown, H. C. and P. K. Jadhav (1983). Asymmetric Hydroboration. Asymmetric Synthesis. J. D. Morrison. New York, AP. 2: 1. Lecture Number 8 Olefin Addition Reactions–1 Problems of the Day: (To be discussed) Hydroboration Rationalize the stereochemical outcome of this reaction OH Epoxidation Directed Epoxidation 9-BBN OH OH Me CH H O