猪肉中13种磺胺类药物多残留检测超高效液相_串联质谱法.pdf

, 2009, 11( S1) : 35 - 38 Journa l of A gr icu ltura l Sc ience and T echno logy 13 - 严 凤, 曹 莹, 李丹妮, 张文刚, 蒋 音, 张 鑫, 顾 欣 ( , 201103) : - , , , - 0. 25 Lg / kg , : - : S816. 17 : A : 100 8-0 864 ( 2009) S1-0035-04 SimultaneousDeterm ination of 13 Sulfonam ides inPorcine M eatbyUltra Performance Liquid Chromatography- Tandem Mass Spectrometry YAN F eng, CAO Y ing, L I D an-ni, ZHANG W en-gang, JIANG Y in, ZHANG X in, GU X in ( Sh anghai Superv isory Inst itu te of V eterin ary D rug s and F eed staff, Sh anghai 20 1103, Ch ina) bstract: A ultra pe rfo rm ance liqu id chrom atog raphy- tandem m ass spectrom etr ic ( U PLC /M S /M S ) m ethod w as developed for smi ultaneou s determ ina tion o f 13 sulfonam ides in the po rc ine m eat. Com ponents w ere ex tracted from hom ogen ized samp le w ith acetonitrile, de fatted by n-hexane and further extracted by A lum ia B. T he lmi it o f determ ination ( LOD ) w as 0. 25 Lg / kg. The m ethod w as proved to be satisfactory in prec ision, securacy and sen sitiv ity for m ulti-residu es de term ination. K ey words: su lfonam ide residu es analysis u ltra pe rfo rm ance liqu id chrom atography- tandem m ass sp ectrom etry ( sulfonam ides, SA s) [ 1] , , U PLC /M S /M S , , , 1 [ 2 ] , 1. 1 SA s ( U ltra P erform ance L iqu id , Chrom tography, U PLC) , W aters , ( Qu attro P rem ier XE ), W ater