妇科良性肿瘤腹腔镜子宫全切术及开腹子宫全切术疗效对比及对机体免疫功能影响.doc

妇科良性肿瘤腹腔镜子宫全切术及开腹子宫全切术疗效对比及对机体免疫功能影响 　　[摘要] 目的 分析?D科良性肿瘤腹腔镜子宫全切术与开腹子宫全切术的疗效及对机体免疫功能的影响。 方法 选择2010年11月～2014年9月湖北省第三人民医院妇产科收治的因妇科良性肿瘤需行子宫全切术的患者68例为研究对象，依据手术方式不同分为观察组和对照组，观察组36例患者行腹腔镜子宫全切术，对照组32例患者行开腹子宫全切术，比较两组患者术中和术后情况及术前1 d、术后1 d、术后3 d血清IgG、C3、白介素（IL）-2及IL-4水平。 结果 观察组患者术中出血量显著少于对照组，术后排气时间及术后住院天数均显著短于对照组（P 0.05）。 结论 腹腔镜子宫全切术应用于妇科良性肿瘤能够显著减少术中出血量，缩短术后排气时间及术后住院天数，减小对机体免疫功能的影响，值得临床推广应用 [关键词] 良性肿瘤；腹腔镜；子宫全切术；免疫功能 [中图分类号] R737.3 [文献标识码] A [文章编号] 1673-7210（2016）11（b）-0086-04 [Abstract] Objective To analyze the efficacy of benign gynecologic treated by laparoscopic hysterectomy and abdominal hysterectomy and its effect on immune function. Methods 68 patients with benign gynecologic needed to undergone hysterectomy from November 2010 to September 2014 in Gynaecology and Obstetrics Department， the Third People′s Hospital of Hubei Province were selected as study objects. They were divided into observation group and control group according to the operation scheme， laparoscopic hysterectomy was used in observation group of 36 patients and abdominal hysterectomy was applied in control group of 32 patients. Intraoperative and postoperative conditions， IgG， C3， IL-2 and IL-4 levels preoperative 1 d and postoperative 1 and 3 d between two groups were compared. Results Intraoperative blood loss of observation group was less than that of control group， postoperative exhaust time and hospital stay of observation group were shorter than those of control group （P 0.05）. Conclusion Laparoscopic hysterectomy applied to benign gynecologic can significantly reduce intraoperative blood loss， shorten postoperative exhaust time and hospital stay， reduce the impact on the immune function， it is worthy of clinical popularization and application. 　　[Key words] Benign tumor； Laparoscopy； Hysterectomy； Immune function 妇科肿瘤是女性常见疾病，其发病率逐渐升高，严重威胁女性的生命健康及生活质量，手术治疗作为主要的治疗策略[1-2]，与手术直接相关的并发症越发引起重视。随着微创手术的开展及腹腔镜技术的成熟，腹腔镜手术在妇科临床工作中被广泛应用[3]，腹腔镜技术避免了腹腔脏器与外界环境的直接接触，能最大限度地缩小手术切口，在保证手术疗效的同时满足现代女性对于美学