扁桃体切除对伴有慢性扁桃体炎慢性肾炎患者长期疗效及安全性观察.doc

扁桃体切除对伴有慢性扁桃体炎慢性肾炎患者长期疗效及安全性观察 　　【摘要】 目的：了解扁桃?w切除对伴有慢性扁桃体炎的慢性肾炎的长期疗效和安全性。方法：选择合并慢性扁桃体炎的尿常规蛋白≤2+的且肾功能正常的慢性肾炎患者121例，排除了继发性肾病，在医师建议和患者自愿的原则下将患者分为两组，扁桃体切除组52例，非扁桃体切除组69例，随访3年，观察收集上述患者的尿常规+沉渣镜检、24 h尿蛋白定量、呼吸道感染等情况。结果：扁桃体切除组资料较完整者41例，非扁桃体切除组资料较完整者56例。随访3年时两组24 h蛋白尿和血尿均下降，扁桃体切除组下降尤其明显，差异均有统计学意义（P0.05）。结论：扁桃体切除对于病情相对较轻的伴有慢性扁桃体炎的慢性肾炎患者有较好远期疗效和安全性 【关键词】 扁桃体炎； 慢性肾炎； 疗效 doi：10.14033/j.cnki.cfmr.2016.33.003 文献标识码 A 文章编号 1674-6805（2016）33-0006-03 【Abstract】 Objective：To investigate the long-term efficacy and safety of tonsillectomy for chronic nephritis with chronic tonsillitis.Method：121 patients with chronic nephritis of urine protein ≤2+ and normal renal function with chronic tonsillitis were selected，secondary nephropathy was excluded，and under the principle of voluntary these patients were divided into two groups，52 cases in tonsillectomy group，69 cases in non tonsillectomy group.They were followed for 3 years and the data of routine urine sediment microscopy，24 hours urine protein，respiratory tract infection etc were observed.Result：There were 41 patients with whole data in the tonsillectomy group，56 patients with whole data in the non tonsillectomy group.During three years of follow-up，24 h proteinuria and hematuria of patients in the two groups decreased，fairly obvious in the tonsillectomy group，the differences were statistically significant（P0.05）.Conclusion：Tonsillectomy for the relative light condition of chronic tonsillitis with chronic nephritis has good long-term efficacy and safety. 　　【Key words】 Tonsillitis； Chronic nephritis； Efficacy First-author’s address：The Affiliated Hospital of Putian College，Putian 351100，China 慢性肾炎多数迁延不愈，特别是伴有慢性扁桃体炎者，有时候很难控制病情，渐进性发展为慢性肾衰竭。国内有关扁桃体切除治疗肾炎的文献多数是针对IGA肾病患者近期疗效观察，远期疗效安全性研究甚少。因此，笔者对伴有慢性扁桃体炎的慢性肾炎患者，行扁桃体切除术，随访3年，以了解扁桃体切除对伴有慢性扁桃体炎的慢性肾炎的长期疗效和安全性 1 资料与方法 1.1 一般资料 选取2009年1月-2013年6月尿常规蛋白≤2+的且肾功能正常的合并慢性扁桃体炎的慢性肾炎患者121例，排除乙肝、丙肝、红斑狼疮、过敏性紫癜、糖尿病等继发性肾病，请耳鼻喉科医生会诊，在医师建议和患者自愿的原则下将患者分为两组，扁桃体切除组52例，非扁桃体切除组69例，之后进行随访 随访3年后，扁