Binswanger病遗传度的研究_陈春富.pdf

1997 4 14 2 85 Binsw anger 陈春富　贾海燕　薛慎伍　郭述苏　赵修义 曹　霞　陈　晶　葛树叶　于金萍　李　怡 Binswanger , , 82 Binsw anger 11( 10. 30% ) ( 2. 85% ) , 54. 35% 8. 28% Binsw anger Binsw anger HERITABILITY OF BINSWAN GER S DI SEASEChen Ch unf u , J ia H aiy an , X ue Shenw u , et al . D ep ar tment of N eur ology , J inan M ilitary General H osp ital , J inan 250031 Abstract T he role of hereditary fact or in the etiology of Binsw anger s disease was e plored w ith a - . 82 design of case control study based on family line investigation T he subject consisted of cases of Binsw anger s disease mat ched w ith 82 controls. T he results show ed that the prevalence rate of the probands first relative ( 10. 30% ) w as significantly higher than that of the cont rols ( 2. 85% ) . T he heri- tability of Binsw anger s disease w as 54. 35% 8. 28% . T here w as on significant difference of prevalence rate bet ween male and female. T he authors conclude that genetic factor play s certain role in Binsw anger s disease. Key wordsBinswangers diseaseHerit abilityCase-cont rol study ( ) , Binsw anger BD BD [ 1] , , 1990 BD , BD 8 1995 8 82 BD , 1 : 250031 , (