2014V2结直癌治疗指南.ppt

NCCN（2014.V2)结直肠癌治疗指南解读;圭狱缘瞅弗鸥砌棍真章腰激蚌玉益蕊要铺匪乏贝流洱屠兵臆糙幕硫帧蕉巴2014V2结直癌治疗指南2014V2结直癌治疗指南;息肉样癌 无远处转移的结肠癌 同时性远处转移的结肠癌 无远处转移的直肠癌 同时性远处转移的直肠癌 进展期及转移性结直肠癌化疗 结直肠癌手术原则 肝肺转移灶的外科处理原则 病理评估原则 术后随访 术后复发癌的处理原则 XELOX方案在结直肠癌辅助治疗中的价值;定义：;无远处转移的结肠癌（Colon cancer without metastasis）;同时性远处转移的结肠癌（Colon cancer with synchronous metastasis ）;同时性远处转移的结肠癌（Colon cancer with synchronous metastasis ）;无远处转移的直肠癌（Rectal cancer without metastasis）;无远处转移的直肠癌（Rectal cancer without metastasis）;同时性远处转移的直肠癌（Rectal cancer with synchronous metastasis ）;进展期及转移性结直肠癌化疗（Chemotherapy for advanced or metastatic disease）;结直肠癌手术原则（Principles of surgery for colorectal cancer）;肝肺转移灶的外科处理原则（Principles of surgery for colorectal metastasis）;病理评估原则(Principles of pathologic review);术后随访（Postoperative surveillance）;术后复发癌的处理原则（ Workup and treatment for recurrence）;术后复发癌的处理原则（ Workup and treatment for recurrence）;XELOX——结直肠癌患者辅助化疗的标准方案;;;XELOX方案的血液学毒性显著低于FOLFOX方案;McCleary N.A.J, Meyerhardt J, Green E, et al. Impact of older age on the efficacy of newer adjuvant therapies in ＞12,500 patients (pts) with stage Ⅱ/Ⅲ colon cancer: Findings from the ACCENT Database. J Clin Oncol 27:15s, 2009 (suppl; abstr 4010). Haller DG, Tabernero J, Maroun J, et al. Capecitabine Plus Oxaliplatin Compared With Fluorouracil and Folinic Acid As Adjuvant Therapy for Stage Ⅲ Colon Cancer [J]. Official Journal of the American Society of Clinical Oncology, 2011, 11(29): 1465 - 71.;远期疗效相当 老年患者也可获益 毒性更小 使用方便 患者依从性好;谢谢！