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3p87(新版)使用说明(国外英文资料)
3p87(新版)使用说明(国外英文资料)
3p87 (New Edition) instructions
One of the basic requirements.
In 1. sampling design based on the reasonable for intravenous injection, a model of not less than five, two compartment model of not less than eight, a three compartment model of eleven different time blood drug concentration data. For after intravenous injection and intravenous infusion of drug, a model room not less than four, two compartment model of not less than five, not less than three compartment model of nine different time blood drug concentration data.
2. IBM-PC and compatible models of microcomputers, English DOS operating system, the printer.
Two. Call 3P87 program preparation work before
Identify 1. main data. If a dose of several individuals, the main data refers to the concentration data of mean or median, or user that concentration of the most representative data. In general, the intravenous injection of data with mean or median is suitable for non intravenous administration can be considered using the measured point data based multi data. In order to calculate the individual data, the calculation results can refer to the main data, select the compartment number and weights were calculated.
Figure 2. curve printing preparation. See the file available DQX.TXT printer to print out, namely the executive order PRINT AQX.TXT
The three call to 3P87.
The 3P87 program into the A disk drive, type A:3P87 and press enter, the page display program, and then press any key to show the main menu program:
The main menu
1. input or modify data
The pharmacokinetic parameters were calculated with 2. main data
3. the multiple data batch calculation
4. conditions specified by the user algorithm and calculate the pharmacokinetic parameters
The calculation results of 5. output
The pharmacokinetic parameters were calculated by a simplified system 6.
Figure 7. pharmacokinetic compartment model and description
8. out of the 3P87 program
Four. Input or modify data
The procedures in the main me
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