Degos病一例并文献复习(国外英文资料).doc

Degos病一例并文献复习(国外英文资料) Degos is an example and review the literature 2010-05-25, wu xiun xiaofeng, the king of guo wendong 【 abstract 】 objective to explore the etiology, pathogenesis, clinical manifestations, diagnosis and differential diagnosis of Degos. Methods the pathological characteristic of the small intestine and the ulcer disease were reported by the method, and the pathological characteristic of the lesion was analyzed and the literature was reviewed. Results in addition to the typical wedge skin, subcutaneous tissue necrosis, BingBianChu swollen endothelial cell proliferation and luminal stenosis or occlusion, a majority of lymphocyte infiltration around blood vessels. Conclusion Degos is a systemic necrotizing vasculitis. In clinic, Degos should be considered for patients with impaired skin lesions. 【 keywords 】 Degos disease (malignant atrophic papulosis) small intestine perforated angiitis Degos: a case report and review of literature WU Xir UN, LI Xiaofeng, XIAO Jinmei, et al. The Second Hospital, Shanxi Medical University, T aiyuan 030001 【Abstract】　Objective　To explore the etiology ,pathogenesis,clinical manifestation,diagnosis and differential diagnosis of Deg os′ disease.Methods　Pathognomonic skin lesions of Degos′disea se,accompanied by small bowel perforation and gastric ulcer in a 37-year-old woman,were reported. Histopathological features of skin lesions were studied.The literature related to Degos′ disease was reviewed.Results　The studies of skin histopothological study showed the typical wedge-shaped regions of necrobiosis and lymphocyte inflammatory infiltration.There were endothelial proliferation,swelling and fibrinoid necrosis in small dermal vessels with narrow ing of the lumina,thrombosis,obstruction,and perivascular lymphocyte infiltratio n in the subcutaneous arterioles of the skin lesions.Conclusion　Degos′disease is a systemic necrotizing vasculitis.Degos′disease should be c onsidered in the differential diagnosis of skin lesions a