粉体学和流变学34126.ppt

粉体学和流变学;第一节 粉体学概述;二、粉体粒子大小;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;（一）粒子大小;（二）粒子径的测定方法;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;;（三）粒度分布;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;三、粉体粒子的比表面积;四、粉体的密度、孔隙率;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;五、粉体的流动性;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;粉体的充填;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;（二）影响粉体流动性的因素;吸湿性;临界相对湿度(CRH);水溶性药物的吸湿平衡曲线 1-尿素 2-枸橼酸 3-酒石酸 4-对氨基水杨酸钠;CRH湿水溶性药物的特征性参数，几种水溶性药物混合后，其吸湿性有如下特点：混合物CRH约等于各组分的乘积，即 CRHAB = CRHA × CRHB 测定CRH有如下意义：（1）CRH可作为药物吸湿性指标。（2）控制生产、储藏的环境条件。（3）为选择防湿性辅料提供参考。 ;非水溶性药物（或辅料）的吸湿平衡曲线 1-合成硅酸铝 2-淀粉 3-硅酸镁 4-天然硅酸铝 5-氧化镁 6-白陶土 7-滑石 ;（三）改善流动性的方法;润湿性;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;粉体的压缩;压缩成形性;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd.;第二节、流变学概述;第二节、流变学概述;第二节、流变学概述;剪切应力与剪切速度;图14-1流动时形成速度梯度;剪切应力与剪切速度;流变性质; (a)牛顿流动