2型糖尿病并发脑梗死影响因素分析2.doc

影响2型糖尿病患者并发脑梗死的危险因素分析（P0.05.01）type 2 diabetes with cerebral infarction Rao Gao-feng,Chen En-fu,Song She-geng ,Wu Jin-you,Cai Hai-bo,Yan Cheng-hong The First People Hospital of Wenling City in Zhejiang Province, Wenling 317500, China [Abstract] Objective To analysis on the risk factor in T2DM with cerebral infarction. Method 125 patients with T2DM were selected in our study and divided into 2 groups:diabetes mellitus associated with cerebral infarction (DMCI group ,n=65);diabetes mellitus non-cerebral infarction(DMNCI group ,n=60). 45 healthy individuals served as controls（control group,n=45). and disease history and laboratory examination were collected and analyzed。The extracranial carotid arteries of the whole cases were examined by high-frequency color Doppler ultrasonography,the differences of intima-media thickness of the carotid arteries(IMT), atherosclerotic plaque incidence in three groups were 基金项目：温岭市科技局资助项目（2008WLCA0049） compared. Result IMT of patients in DMCI group was significantly thicker than patients in DMNCI group and control group （P0.05）.The incidence of carotid artery atherosclerosis plaque of patients in DMCI group was significantly higher than patients in DMNCI group and control group（P0.05).moreover result of those are same in DMNCI group and control group（P0.05).Hypertension history,BMI、levels of SBP、DBP、FPG、HbA1C、CRP、TG、TC、LDL-C MA and HDL-C in DMCI group showed statistically significant difference with those in group DMNCI group and control group（P0.05 or 0.01)．Conclusion IMT，incidence of carotid artery atherosclerosis plaque，Hypertension history，BMI、levels of SBP、DBP、FPG、HbA1C、TG、TC、LDL-C MA and HDL-C were the risk factors of type 2 diabetes combined with cerebral infarction. [Key words] type 2 diabetes；；,致使脑组织供血不足而发生缺血、缺氧而引起。流行病学调查发现，糖尿病患者患心脑血管疾病的相对危险度是非糖尿病患者的2～3 倍，而脑梗塞是糖尿病的常见并发症和主要死因之一。据统计，糖尿病合并脑梗塞的危险性是非糖尿病者的2-4 倍，病死率高[2]。全面防治2型糖尿病并发脑梗塞危险因素至关重要。本文对本院2010 年1月至2013年1月收治的2型糖尿病并发脑梗死患者的临床资料进行分析，探讨其间关系及其高危影响因素