国际癫痫诊断分类新框架-培训课件.ppt

* * * So new concepts and terminology for organizing the epilepsies have been recommended. This is an ORGANIZATION rather than a Classification as we are not realistically at the point at which we can classify according to the biology of these disorders in a scientific way. In this presentation we will discuss what we have done in the new organization. * * Changes in the new organization are structural and in general do not affect diagnostic entities. Here are the key items we will work through. * * * * * * Here is a diagram that shows a conceptual network for generalized seizures involving the corticothalamic circuitry. Theoretically a generalized seizure could start at different points in the network and engage bilaterally distributed networks. Thus a seizure could start frontally or even parietally.The key point is that a generalized seizure can start from a focal point. * * Here is a diagram that shows a conceptual network for generalized seizures involving the corticothalamic circuitry. Theoretically a generalized seizure could start at different points in the network and engage bilaterally distributed networks. Thus a seizure could start frontally or even parietally. Here the conceptual diagram of the network is superimposed on a functional MRI of generalized spike wave activity. * * The organization of generalized seizures has actually been simplified from 1981 and 2006 * * * * Syndrome names retain the word “benign” eg. benign familial neonatal seizures, benign childhood epilepsy with centro temporal spikes * 国际癫痫诊断分类2010新框架  2010 Proposal for Revised Terminology for Organization of Seizures and Epilepsies 北京大学第一医院儿科 秦 炯 ILAE国际癫痫分类体系 癫痫发作的国际分类 1960首次发布 1964年修订 1970年修订 1981年定型 2001年再修订 2006-分类工作组报告 2010-术语和概念修订 …… 国内1983 癫痫综合征的国际分类 1984年提出 1989年定型 2001年再修订 2006 2010 …… ILAE建立国际分类的目的 建立命名和分类的国际共识 主要用于临床目的（治疗） 旨在反映各术语和类型的基本关系 2005-2009 ILAE Commission ReportEpilepsia 2010;51:676-685 发作及癫痫分类的术语与概念Terminology and Concepts for Classification of Seizures