急性胰腺炎患者生化（白蛋白、钙、糖、C.docxVIP

急性胰腺炎患者生化（白蛋白、钙、糖、C关键词：胰腺炎；白蛋白；血钙；血糖；C-反应蛋白；血钾　　【摘要】 目的 探讨急性胰腺炎（AP）急性期（发病48h内）血浆白蛋白（ALb）、血糖（Glu）、血钙（Ca2+）、C-反应蛋白（CRP）、血钾（K+）的变化，预测、评估AP严重程度及临床意义，以指导临床治疗。方法 随机抽取既往无特殊病史的急性胰腺炎（发病48h内就诊）135例，其中重症急性胰腺炎（SAP）55例，轻型急性胰腺炎（MAP）80例，使用全自动生化分析仪，分别测定Alb、G1u、Ca2+ 、CRP及K+水平变化并进行比较。结果 急性期SAP组和MAP组的Alb、Ca2+ 及 K+均降低，但SAP组的Alb及Ca2+水平较MAP显著降低，P＜0．05；SAP组与MAP组的CRP及G1u水平均升高，但SAP组的C-RP及G1u水平较MAP组显著升高，P＜0．05；急性期SAP和MAP组的K+变化差异无显著性，Pgt;0．05。结论 急性胰腺炎急性期血Alb、G1u、Ca2+及CRP变化与AP严重程度呈正相关，其可以作为评价AP严重程度的指标，并能指导临床治疗；K+与AP的严重程度无相关性，不能作为评价AP严重程度的指标。　　【关键词】 胰腺炎；白蛋白；血钙；血糖；C-反应蛋白；血钾　　Biochemical changes （albumin， calcium，glucose,C-reactive protein， potassium）and clinical significance of acute pancreatitis　　　　【Abstract】 Objective To investigate the changes of albumin，glucose，Ca2+， C-reactive protein，K+ in the acute stage of acute pancreatitis predict and evaluate the degree and clinical value to guide clinical treatment.Methods 135 acute pancreatitis patients with heath previously within 48 hours after onset were involved and divided into two groups randomly: severe acute pancreatitis group（SAP n= 55）and mild acute pancreatitis group （MAP n=80）.The value of albumin，glucose，Ca2+， C-reactive protein and K+was measured in fully automatic biochemical analyzing equipment. Results The value of albumin, Ca2+ ， K+decreased in two groups， but the value of albumin and Ca2+decreased more in SAP group than MAP group（Plt;0.05）;The value of C-reactive protein and glucose was increased in two groups， but SAP group increased more C-reactive protein and glucose than MAP group did（Plt;0.05）; The value of potassium had no difference between SAP group and MAP group.Conclusions The value of albumin，glucose，Ca2+， C-reactive protein was positive to the degree of acute pancreatitis and could evaluate the degree of acute pancreatitis， guide clinical treatment，but value of K+was not related with the degree of acute pancreatitis.　　【Key words】 pancreatitis;albumin;glucose;Ca2+;C-reactive protein;K+　　急性胰腺炎是胰腺的急性炎症过程，起病急骤，