中国药科大学药学专业英语课件-六味地黄丸.ppt

六 味 地 黄 丸 Liuwei Dihuang Pills Ingredients Radix Rehmanniae Preparata 160 g 熟地黄 Fructus Corni (processed) 80g 山茱萸（制） Cortex Moutan 60 g 牡丹皮 Rhizoma Dioscoreae 80 g 山 药 Poria 60 g 茯 苓 Rhizoma Alismatis 60 g 泽 泻 Procedure/制法 Pulverize the above six ingredients to fine powder, sift and mix well. To each 100 g of the powder add 35～50 g of refined honey and a quantity of water to make pills and dry; alternatively add 80～110 g of refined honey to make small honeyed pills or big honeyed pills. Description Brown-black water-honeyed pills, black-brown small honeyed pills or big honeyed pills; taste, sweet and sour. Identification Microscopical: Starch granules triangular-ovoid or oblong, 24～40μm in diameter, hilum short cleft or V-shaped. Irregular branched masses color less, dissolved in chloral hydrate solution: hyphae colorless, 4～6μm in diameter. Parenchyma greyish-brown to black-brown, cells mostly shrunken, and each containing a brown nucleus-like mass. Clusters of calcium oxalate occurring in colourless parenchymatous cells, sometimes several clusters arranged in rows. Epidermal cells of pericarp orange-yellow, polygonal in surface view, with somewhat beaded anticlinal walls. Parenchymatous cells subrounded, with elliptical pits, gathered into pit groups. (2) Physical and Chemical identification To 9 g of small honeyed pills or big honeyed pills, or 6 g of water-honeyed pills, in powder, add 4 g of kieselguhr and triturate well. Heat under reflux with 40 ml of ether at a low temperature for 1 hour, filter and evaporate to remove ether. Dissolve the residue in 1 ml of acetone as the test solution. Dissolve paeonol CRS in acetone to produce a solution containing 1 mg per ml, as the reference solution. Carry out the method for thin layer chromatography (Appendix Ⅵ B), using silica gel G as the coating substa