有机合成(英)A.docVIP

Homewark Ⅰ.Translate the following term into Chinese (10 Points) Acid-catalyzed condensation Pericyclic reaction Primary alkyl halide Nucleophilic addition Ethylene oxide Monosubstituted benzene Diazo group Beckmann rearrangement Dithioacetal Potassium permanganate Ⅱ. Select the correct choice, only one choice is correct ( 20 Points ). 1．The commonly used bases, in order of decreasing base-strength, are (a) NH2－ OH－ OMe－ EtO－ (b) EtO－ OH－ R3N NH2－ (c) NH2－ Ph3C－ MeO－ OH－ (d) NH2－ Me3CO－ MeO－ OH－ 2 The condition for following reaction is: (a) ABIN (b) base (c) h( (d) heat 3．Which of the following compounds is inert towards amines or ammonia in SN2 processes ? (a) (b) CH3CH2Br (c) CH2=CHCH2Br (d) 4. Which of the following compounds is enol ? (a) (b) (c) (d) CH3CH2OH 5. As show in the figure , Y is a substituent, which of the following substitutents (Y group) is the most activing group in Electrophilic Aromatic Substitution ? (a) OR (b) Br (c) CN (d) CH3 6. The reaction belongs to which of the following reaction ? (a) Electrophilic Aromatic Substitution (b) Friedel－Crafts reaction (c) Chloromethylation reaction (d) Nucleophilic Aromatic Substitution 7. The reaction via which of the following intermediates ? (a) anion (b) cation (c) free readical (d) benzyne 8.. As show in the following reaction, the aryl group provide anchimeric assistance to the reaction. Which of the substituents in the aromatic ring give rise to greatest rate of migration ? (a) p－NH2 (b) p－Br (c) p－CN