- 1、本文档共26页,可阅读全部内容。
- 2、有哪些信誉好的足球投注网站(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
谢 谢! * * BACKGROUND: The authors analyzed the outcome of patients with early-stage breast carcinoma after an isolated local recurrence, taking into account initial tumor characteristics and the type of initial treatment and local salvage treatment. METHODS: One hundred five patients were studied who presented with a breast tumor measuring or= 25 mm and who subsequently developed an isolated local recurrence (breast or chest wall) as the first tumor event. A second series included 335 patients who developed distant metastases as the first event. Cox models that took into account potential prognostic factors were used to estimate the risk of death. First, survival rates were compared after an isolated local recurrence and after a diagnosis of distant metastases; and, second, effects of initial treatments and local or systemic treatments of local recurrences were analyzed. RESULTS: The 10-year survival rate was 56% (95% confidence interval, 45-65%) after an isolated local recurrence compared with 9% (95% confidence interval, 7-13%) after distant metastasis as the first event. Three independent prognostic factors for the risk of death after local recurrence were identified: histologic tumor grade, patient age at the time of diagnosis with the primary tumor, and disease free interval until recurrence. The type of initial treatment and local salvage treatment did not influence the risk of death. Systemic treatments of local recurrence had different effects according to the patients menopausal status. In premenopausal patients, ovarian suppression and chemotherapy significantly decreased the risk of death. In postmenopausal women, systemic treatments did not affect the risk of death. CONCLUSIONS: Isolated local recurrences in patients with early-stage breast carcinoma carry a moderately good prognosis. The outcome of patients is not affected by the type of initial treatment or local salvage treatment. After a local recurrence, ovarian suppression or chemotherapy had a bene
您可能关注的文档
- AmtaxCompact哈希在线氨氮分析仪使用说明书及培训手册.ppt
- ANSOFT12静磁场分析案例解析.ppt
- Ansys-Workbench基础.ppt
- ANSYSDYNA教程.ppt
- ansys002有限元分析(FEA)方法.ppt
- ansysworkbench屈曲分析讲义.pptx
- AnsysWorkbench教程有限元.ppt
- ansys电磁场分析教程chapter-3-1.ppt
- ANSYS空间问题分析方法.ppt
- ansys简介及转轴模态分析实例.ppt
- 2025年中国二氧化硒行业市场发展前景及发展趋势与投资战略研究报告.docx
- 2025年中国白榉直纹贴面板行业市场发展前景及发展趋势与投资战略研究报告.docx
- Unit7+重点知识清单总结-2024-2025学年冀教版英语九年级全册.docx
- 食盐项目绩效评估报告.docx
- 年产130万套家具生产线项目可行性研究报告模板-立项拿地.doc
- 2025年中国石墨接头行业市场发展前景及发展趋势与投资战略研究报告.docx
- 大学生就业21问学习通测试及答案.pdf
- 年产25万平方米导热绝缘垫片项目可行性研究报告写作模板-备案审批.doc
- 2025(突破训练)023学年第一学期高一年级历史期末测验 .pdf
- 洗衣机电脑程控器项目绩效评估报告.docx
文档评论(0)