医学微生物 辨析题(外国英语资料).doc

医学微生物 辨析题(国外英文资料) Mycobacterium tuberculosis Mycobacterium tuberculosis endotoxin free, do not produce exotoxin and invasive enzymes, the possible pathogenic role of bacteria in the tissue and cell proliferation of strong inflammatory reaction, and to induce delayed hypersensitivity of injury. Mycobacterium tuberculosis can enter the body through the respiratory tract, digestive tract and damaged skin mucosa. It can cause many kinds of tissues and organs, and cause tuberculosis of the corresponding organs. Tuberculosis is the most common. Clostridium difficile (two) pathogenicity and immunity; Clostridium tetani by wound infection, infection and wound conditions, important condition is the formation of anaerobic micro environment: wound wound is narrow and deep, mixed with dirt and impurities; tissue necrosis, ischemia; mixed infection with bacteria or facultative anaerobic bacteria. - - pathogenic substances of tetanus toxoid (exotoxin) As a neurotoxin, strong toxicity, high affinity with the spinal cord and brain stem cells, ganglioside tetanospasmin and CNS inhibitory presynaptic membrane binding, blocking inhibitory mediators, cause nerve sustained excitement, skeletal muscle tonic spasm, muscle tension increases. The disease caused by tetanus - - Incubation period: 7-14 days depending on the distance between the wound and the CNS Clinical manifestation: muscle tetanic contraction, trismus and dysphagia, wry face, opisthotonos, clonic seizures, severe asphyxia death due to respiratory muscle spasm. The immune system is not strong after the disease. (three) microbiological examination and Prevention Typical symptoms and medical history can be diagnosed. Prevention: timely debridement, to prevent the formation of anaerobic micro environment. The vaccine, DPT vaccine, which may lead to the injury of tetanus antitoxin, emergency injection, the onset of the extensive use of antitoxin and antibiotics. hepatitis B 2, ways of communication Hematogenous transmission Moth